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TNFRSF12A
Gene Name
tumor necrosis factor receptor superfamily, member 12A
Image
Gene Ontology Annotations
Cellular Component
Ruffle
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Molecular Function
Protein Binding
Biological Process
Angiogenesis
Substrate-dependent Cell Migration, Cell Attachment To Substrate
Positive Regulation Of Apoptotic Process
Regulation Of Angiogenesis
Positive Regulation Of Axon Extension
Regulation Of Wound Healing
Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
9 interactors:
PVR
PVRL2
RAC1
SLC30A2
TNFSF12
TRAF1
TRAF2
TRAF3
TRAF5
Entrez ID
51330
HPRD ID
05801
Ensembl ID
ENSG00000006327
Uniprot IDs
Q9NP84
PDB IDs
2EQP
2KMZ
2RPJ
Enriched GO Terms of Interacting Partners
?
Susceptibility To T Cell Mediated Cytotoxicity
Apoptotic Process
Positive Regulation Of Innate Immune Response
Programmed Cell Death
Cell Death
Death
Susceptibility To Natural Killer Cell Mediated Cytotoxicity
Regulation Of Innate Immune Response
Positive Regulation Of Immune Response
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target
Positive Regulation Of Immune Response To Tumor Cell
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Apoptotic Process
Regulation Of Cell Death
Regulation Of Immune Response
Positive Regulation Of T Cell Mediated Immunity
Positive Regulation Of Immune System Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Adaptive Immune Response
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Positive Regulation Of Natural Killer Cell Mediated Immunity
Regulation Of Natural Killer Cell Mediated Cytotoxicity
Regulation Of Natural Killer Cell Mediated Immunity
Regulation Of Adaptive Immune Response
Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of Immune System Process
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cell-cell Junction Organization
Viral Entry Into Host Cell
Entry Into Host Cell
Positive Regulation Of Cell Activation
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Cellular Component Assembly
Coreceptor-mediated Virion Attachment To Host Cell
Positive Regulation Of Sequestering Of Zinc Ion
Regulation Of Defense Response To Virus
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of T Cell Mediated Cytotoxicity
Adherens Junction Organization
Regulation Of T Cell Mediated Cytotoxicity
Immune Response-regulating Signaling Pathway
Cellular Response To Tumor Necrosis Factor
Regulation Of Cell Activation
Signal Transduction
Positive Regulation Of Leukocyte Mediated Cytotoxicity
Interaction With Host
Tagcloud
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2alpha
2beta
abcb1b
additive
biexponential
clearance
designated
dimeric
erb3
fn14
fused
gelonin
hsgz
humanized
id
immunotoxin
inducer
kills
luc
mcf7
mdr
mdr1
pharmacokinetic
synergistic
t1
toxin
translated
tweak