TNFRSF12A

Description		TNF receptor superfamily member 12A
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GO Annotations	Cellular Component	Ruffle Plasma Membrane Cell Surface Membrane
	Molecular Function	Protein Binding
	Biological Process	Angiogenesis Apoptotic Process Substrate-dependent Cell Migration, Cell Attachment To Substrate Cell Adhesion Cell Differentiation Positive Regulation Of Apoptotic Process Regulation Of Angiogenesis Positive Regulation Of Axon Extension Regulation Of Wound Healing Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		TNFR2 non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: KRTAP3-3 RAC1 SLC30A2 TNFSF12 TRAF1 TRAF2 TRAF3 TRAF5
Entrez ID		51330
HPRD ID		05801
Ensembl ID		ENSG00000006327
Uniprot IDs		Q9NP84
PDB IDs		2EQP 2KMZ 2RPJ
Enriched GO Terms of Interacting Partners?		Thioesterase Binding Tumor Necrosis Factor Receptor Binding Tumor Necrosis Factor-mediated Signaling Pathway CD40 Receptor Complex Signaling Adaptor Activity Regulation Of DNA-binding Transcription Factor Activity Regulation Of Canonical NF-kappaB Signal Transduction Ubiquitin Protein Ligase Binding Positive Regulation Of NF-kappaB Transcription Factor Activity CD40 Signaling Pathway Interleukin-17-mediated Signaling Pathway Cytoplasmic Side Of Plasma Membrane Positive Regulation Of DNA-binding Transcription Factor Activity Apoptotic Process Cell Death Programmed Cell Death Cytokine-mediated Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Surface Receptor Signaling Pathway Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Positive Regulation Of Extrinsic Apoptotic Signaling Pathway TORC2 Complex Disassembly MRNA Stabilization Ubiquitin Protein Ligase Activity Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Identical Protein Binding Regulation Of Signal Transduction Regulation Of Apoptotic Signaling Pathway Negative Regulation Of MRNA Catabolic Process RNA Stabilization Positive Regulation Of Ovarian Follicle Development Negative Regulation Of Interleukin-23 Production Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Embryonic Olfactory Bulb Interneuron Precursor Migration Protein Kinase Binding Cerebral Cortex GABAergic Interneuron Development Regulation Of Intracellular Signal Transduction Protein Phosphatase Binding Negative Regulation Of RNA Catabolic Process TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Negative Regulation Of MRNA Metabolic Process Ubiquitin Ligase Complex Regulation Of Cell Communication
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