RSRC1 and GDF9

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RSRC1	GDF9
Description		arginine and serine rich coiled-coil 1	growth differentiation factor 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Speck	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Protein Binding	Cytokine Activity Growth Factor Activity
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing Nucleocytoplasmic Transport RNA Splicing Response To Antibiotic	Oocyte Growth Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth Regulation Of Progesterone Secretion
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Body mass index ( 26426971) Chin dimples ( 27182965) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Depression ( 29700475) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) FEV1 ( 30804560) Height ( 23563607) Left-handedness ( 32989287) Lung function (FVC) ( 30804560) Lung function in heavy smokers (high FEV1 vs average FEV1) ( 26423011) Major depressive disorder ( 27479909) Neuroticism ( 29255261) Sporadic neuroblastoma ( 28545128) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Asthma ( 31619474)
Interacting Genes		8 interacting genes: ACTR3B EEF1A1 GDF9 LSM2 SRPK1 SRPK2 SRRM4 UTP14A	45 interacting genes: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CDKN1A CDKN2C CRELD1 CRIPTO DLEU1 DNM2 FOXG1 FXYD6 GADD45G ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TK1 TRIB3 WASHC3
Entrez ID		51319	2661
HPRD ID		18006	03560
Ensembl ID		ENSG00000174891	ENSG00000164404
Uniprot IDs		Q96IZ7	B4DXG3 O60383
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding RNA Splicing Regulation Of MRNA Processing RNA Processing Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of RNA Splicing Positive Regulation Of Viral Genome Replication Protein-RNA Complex Assembly MRNA Metabolic Process Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication RNA Metabolic Process Positive Regulation Of Viral Process Regulation Of MRNA Metabolic Process Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Regulation Of Progesterone Secretion Regulation Of Viral Life Cycle Eukaryotic Translation Elongation Factor 1 Complex Oocyte Growth Nucleic Acid Metabolic Process Nuclear Speck Organization Regulation Of Viral Process Lsm1-7-Pat1 Complex Regulation Of Female Gonad Development Lsm2-8 Complex Regulation Of Chaperone-mediated Autophagy R-loop Processing U6 SnRNP Host-mediated Activation Of Viral Genome Replication Magnesium Ion Binding Nucleobase-containing Compound Metabolic Process Host-mediated Perturbation Of Viral Genome Replication Kinase Activator Activity Cytoplasmic Side Of Lysosomal Membrane U6 SnRNA Binding	BMP Receptor Activity Transmembrane Receptor Protein Serine/threonine Kinase Activity Cellular Response To BMP Stimulus Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Ossification Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Activin Receptor Activity, Type II BMP Binding Positive Regulation Of Osteoblast Differentiation Tricuspid Valve Morphogenesis Activin Receptor Signaling Pathway Regulation Of Bone Mineralization BMP Signaling Pathway Transforming Growth Factor Beta Receptor Activity, Type I Negative Regulation Of Chondrocyte Proliferation Regionalization Endochondral Bone Morphogenesis Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Developmental Process Positive Regulation Of SMAD Protein Signal Transduction HFE-transferrin Receptor Complex Mitral Valve Morphogenesis RNA Splicing, Via Transesterification Reactions Regulation Of Ossification Pharyngeal Arch Artery Morphogenesis Osteoblast Differentiation Mesenchyme Development Endocardial Cushion Development Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Positive Regulation Of Programmed Cell Death Pattern Specification Process Regulation Of Osteoblast Differentiation Dorsal/ventral Pattern Formation Cellular Response To Growth Factor Stimulus Regulation Of SMAD Protein Signal Transduction Cellular Developmental Process Cell Differentiation SMN-Sm Protein Complex FAR/SIN/STRIPAK Complex Anterior/posterior Pattern Specification Kinase Activity Precatalytic Spliceosome Atrioventricular Valve Morphogenesis Epithelial Cell Proliferation Protein Binding
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