HOXB9 and SFMBT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HOXB9	SFMBT1
Description		homeobox B9	Scm like with four mbt domains 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Binding
	Biological Process	DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development Cell Chemotaxis	Chromatin Organization Regulation Of DNA-templated Transcription Spermatogenesis Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Muscle Organ Development
Pathways
Drugs
Diseases
GWAS		Celiac disease ( 24999842)	A body shape index ( 34021172) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Chronic kidney disease ( 29124443) Creatinine levels ( 29124443) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163 29124443) General cognitive ability ( 29844566) Gout ( 33832965 31578528) Haemorrhoidal disease ( 33888516) Hand grip strength ( 29691431) Height ( 28552196 31562340 31217584) Hip circumference ( 28552196) Hyperuricemia ( 29124443) Intelligence (MTAG) ( 29326435) Mental health study participation (completed survey) ( 31263887) Multiple sclerosis ( 31604244) Schizophrenia ( 28991256 23974872) Serum uric acid levels ( 30993211 29403010 29124443) Type 2 diabetes (age of onset) ( 28060188) Urate levels ( 23263486 31985003 31578528) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		66 interacting genes: BPIFA1 BTG1 BTG2 CALCOCO2 CARD10 CREBBP CYSRT1 EP300 EXOSC8 FAM168B FHL5 GOLGA2 GOLGA6L9 HOPX HOXA1 HSPB2 HSPB2-C11orf52 ING4 KAT2B KRT27 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP17-1 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 LZTS2 MDFI MID2 MTUS2 MYBBP1A NBPF19 NOTCH2NLA OIP5 PCSK5 PFDN5 PHTF1 PLEKHG4 PNMA1 POLR1C RBPMS SAT1 SFMBT1 SIRT1 SPZ1 TAL1 TENM4 TET2 TNS2 TRIM27 TRIP6 ZNF408	12 interacting genes: ACP1 ATOSB CLNK HOXB9 PHC1 PHC2 PSMA1 SCMH1 SPANXN2 SRPK1 WWP2 ZCCHC10
Entrez ID		3219	51460
HPRD ID		00852	09539
Ensembl ID		ENSG00000170689	ENSG00000163935
Uniprot IDs		B3KPJ1 P17482	Q9UHJ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament N-terminal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Protein Acetylation Transcription Coactivator Activity Histone Acetyltransferase Complex Cytosol N-terminal Protein Amino Acid Acetylation Histone H3K27 Acetyltransferase Activity Regulation Of Cellular Response To Heat Histone H3K18 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Diamine N-acetyltransferase Activity Acetyltransferase Activity Structural Constituent Of Skin Epidermis Identical Protein Binding Protein-lysine-acetyltransferase Activity Transcription Corepressor Activity L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Histone Acetyltransferase Activity Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Regulation Of Transcription By Glucose Protein Binding Internal Protein Amino Acid Acetylation Structural Molecule Activity Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Epigenetic Regulation Of Gene Expression Chromatin Remodeling Pre-mRNA Intronic Binding Transcription Initiation-coupled Chromatin Remodeling	PcG Protein Complex PRC1 Complex Histone Binding
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