HOXB9 and TENM4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HOXB9	TENM4
Description		homeobox B9	teneurin transmembrane protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex	Nucleus Cytoplasm Plasma Membrane Membrane Cell Projection Neuron Projection Glutamatergic Synapse
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development Cell Chemotaxis	Gastrulation With Mouth Forming Second Signal Transduction Cell Differentiation Regulation Of Myelination Positive Regulation Of Myelination Central Nervous System Myelin Formation Neuron Development Positive Regulation Of Oligodendrocyte Differentiation Cardiac Muscle Cell Proliferation Cardiac Cell Fate Specification Synaptic Membrane Adhesion Positive Regulation Of Gastrulation
Pathways
Drugs
Diseases
GWAS		Celiac disease ( 24999842)	Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Hair greying ( 26926045) Lactate dehydrogenase levels ( 29403010) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lung cancer in never smokers ( 28604730) Night sleep phenotypes ( 27126917) Right lateral prefrontal cortical growth ( 29682794) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483) Tourette syndrome ( 30818990)
Interacting Genes		66 interacting genes: BPIFA1 BTG1 BTG2 CALCOCO2 CARD10 CREBBP CYSRT1 EP300 EXOSC8 FAM168B FHL5 GOLGA2 GOLGA6L9 HOPX HOXA1 HSPB2 HSPB2-C11orf52 ING4 KAT2B KRT27 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP17-1 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 LZTS2 MDFI MID2 MTUS2 MYBBP1A NBPF19 NOTCH2NLA OIP5 PCSK5 PFDN5 PHTF1 PLEKHG4 PNMA1 POLR1C RBPMS SAT1 SFMBT1 SIRT1 SPZ1 TAL1 TENM4 TET2 TNS2 TRIM27 TRIP6 ZNF408	8 interacting genes: DOCK2 HOXB9 LCE3D LGALS4 PLSCR4 SHFL ZNF587 ZNF696
Entrez ID		3219	26011
HPRD ID		00852	19400
Ensembl ID		ENSG00000170689	ENSG00000149256
Uniprot IDs		B3KPJ1 P17482	Q6N022
PDB IDs			7BAM 7BAN 7BAO 7PLP
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament N-terminal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Protein Acetylation Transcription Coactivator Activity Histone Acetyltransferase Complex Cytosol N-terminal Protein Amino Acid Acetylation Histone H3K27 Acetyltransferase Activity Regulation Of Cellular Response To Heat Histone H3K18 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Diamine N-acetyltransferase Activity Acetyltransferase Activity Structural Constituent Of Skin Epidermis Identical Protein Binding Protein-lysine-acetyltransferase Activity Transcription Corepressor Activity L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Histone Acetyltransferase Activity Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Regulation Of Transcription By Glucose Protein Binding Internal Protein Amino Acid Acetylation Structural Molecule Activity Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Epigenetic Regulation Of Gene Expression Chromatin Remodeling Pre-mRNA Intronic Binding Transcription Initiation-coupled Chromatin Remodeling
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