HOXB9 and HOPX

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		HOXB9	HOPX
Description		homeobox B9	HOP homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex	Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Protein Binding Histone Deacetylase Regulator Activity
	Biological Process	DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development Cell Chemotaxis	Negative Regulation Of Transcription By RNA Polymerase II Trophectodermal Cell Differentiation Bundle Of His Development Regulation Of Transcription By RNA Polymerase II Heart Development Regulation Of Heart Contraction Cell Differentiation Positive Regulation Of Skeletal Muscle Tissue Regeneration Negative Regulation Of Cell Differentiation Lung Alveolus Development Chaperone-mediated Protein Complex Assembly Positive Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Gap Junction Assembly
Pathways			Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS		Celiac disease ( 24999842)	Cadmium levels ( 26025379) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemic sclerosis ( 30247649)
Interacting Genes		66 interacting genes: BPIFA1 BTG1 BTG2 CALCOCO2 CARD10 CREBBP CYSRT1 EP300 EXOSC8 FAM168B FHL5 GOLGA2 GOLGA6L9 HOPX HOXA1 HSPB2 HSPB2-C11orf52 ING4 KAT2B KRT27 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP17-1 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 LZTS2 MDFI MID2 MTUS2 MYBBP1A NBPF19 NOTCH2NLA OIP5 PCSK5 PFDN5 PHTF1 PLEKHG4 PNMA1 POLR1C RBPMS SAT1 SFMBT1 SIRT1 SPZ1 TAL1 TENM4 TET2 TNS2 TRIM27 TRIP6 ZNF408	10 interacting genes: BUB1B EPC1 HDAC2 HOXB9 PICK1 PTGER4 SRF TCF12 TLX3 ZSCAN1
Entrez ID		3219	84525
HPRD ID		00852	06280
Ensembl ID		ENSG00000170689	ENSG00000171476
Uniprot IDs		B3KPJ1 P17482	Q9BPY8
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament N-terminal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Protein Acetylation Transcription Coactivator Activity Histone Acetyltransferase Complex Cytosol N-terminal Protein Amino Acid Acetylation Histone H3K27 Acetyltransferase Activity Regulation Of Cellular Response To Heat Histone H3K18 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Diamine N-acetyltransferase Activity Acetyltransferase Activity Structural Constituent Of Skin Epidermis Identical Protein Binding Protein-lysine-acetyltransferase Activity Transcription Corepressor Activity L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Histone Acetyltransferase Activity Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Regulation Of Transcription By Glucose Protein Binding Internal Protein Amino Acid Acetylation Structural Molecule Activity Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Epigenetic Regulation Of Gene Expression Chromatin Remodeling Pre-mRNA Intronic Binding Transcription Initiation-coupled Chromatin Remodeling	Response To Dopamine Chromatin Sequence-specific Double-stranded DNA Binding Response To Oxygen Levels Eyelid Development In Camera-type Eye Long-term Synaptic Depression Response To Catecholamine Animal Organ Development Monoamine Transport Response To Amphetamine DNA-binding Transcription Factor Binding Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Synaptic Transmission Response To Cocaine DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Response To Amine Norepinephrine Secretion Catechol O-methyltransferase Activity Cellular Response To Nutrient Levels Response To Alcohol Response To Hormone Developmental Process Positive Regulation Of Male Mating Behavior Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Negative Regulation Of Eosinophil Extravasation Serum Response Element Binding Cellular Developmental Process Negative Regulation Of Cellular Component Organization Response To Decreased Oxygen Levels Cellular Response To Phosphate Starvation Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Negative Regulation Of Cell Motility Negative Regulation Of Cell Migration Protein De-2-hydroxyisobutyrylase Activity Regulation Of RNA Biosynthetic Process Negative Regulation Of Eosinophil Migration Bronchus Cartilage Development Cis-regulatory Region Sequence-specific DNA Binding Lung Smooth Muscle Development Negative Regulation Of Locomotion Response To Alkaloid Mitotic Checkpoint Complex Meiotic Sister Chromatid Cohesion, Centromeric Habituation Mastication Renal Sodium Excretion Renal Albumin Absorption Renin Secretion Into Blood Stream
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