RXFP3 and TTC19

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		RXFP3	TTC19
Description		relaxin family peptide receptor 3	tetratricopeptide repeat domain 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Mitochondrion Mitochondrial Inner Membrane Centrosome Membrane Midbody
	Molecular Function	G Protein-coupled Receptor Activity Galanin Receptor Activity	Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Cytokinesis	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly Cell Division
Pathways		G alpha (i) signalling events Relaxin receptors	Complex III assembly
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes		10 interacting genes: APP ENO1 GNAS HSP90B1 KATNB1 NCKIPSD RLN3 TMEM248 TTC19 YWHAE	44 interacting genes: AGXT APRT ATXN1 CCDC33 CHMP4A CIMIP1 COA6 CYSLTR2 DMRT3 EIF4ENIF1 FAM136A FAM217B FH FTO GORASP2 GPANK1 HOXD12 HPS6 IHO1 L3MBTL3 LDB2 MLN MXRA8 NAB2 NME4 POU6F2 PRR35 RBP1 REL RUSC1 RXFP3 SH2D4A SHISA6 SLC67A1-AS SMG9 SPRED1 TBX2 TCAP UBA1 UPF3B USP20 USP54 WASHC1 ZNF688
Entrez ID		51289	54902
HPRD ID		17979	07899
Ensembl ID		ENSG00000182631	ENSG00000011295
Uniprot IDs		Q9NSD7	Q6DKK2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Toll-like Receptor Signaling Pathway Cellular Response To Manganese Ion Response To Manganese Ion Cellular Response To Catecholamine Stimulus Response To Catecholamine Low-density Lipoprotein Particle Receptor Binding Midbody Positive Regulation Of ATP Metabolic Process Regulation Of System Process Protein Phosphatase Inhibitor Activity Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Regulation Of Multicellular Organism Growth Acetylcholine Receptor Activator Activity Regulation Of Defense Response Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process G Protein-coupled Receptor Binding Protein Heterodimerization Activity Lipoprotein Particle Positive Regulation Of Protein Import Mu-type Opioid Receptor Binding Actin Rod Assembly Regulation Of Heart Rate By Hormone ATPase Regulator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Immune Response Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Protein Transport Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Protein Phosphatase Binding Melanosome Trans-Golgi Network Membrane Regulation Of Innate Immune Response Positive Regulation Of Cellular Component Organization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
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