RXFP3 and TMEM248

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		RXFP3	TMEM248
Description		relaxin family peptide receptor 3	transmembrane protein 248
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Membrane
	Molecular Function	G Protein-coupled Receptor Activity Galanin Receptor Activity	Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Cytokinesis
Pathways		G alpha (i) signalling events Relaxin receptors
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: APP ENO1 GNAS HSP90B1 KATNB1 NCKIPSD RLN3 TMEM248 TTC19 YWHAE	27 interacting genes: ANKRD46 ARL6IP1 ARLN BARD1 BRICD5 CLDN19 FAM3C GPR25 GPR37L1 GRM2 LEPROTL1 LHFPL5 MAL MALL RUSF1 RXFP3 SLC35B2 SLC41A1 SYNE4 SYS1 TMEM147 TMEM239 TMEM86B TRARG1 VSTM1 YIF1A YIPF1
Entrez ID		51289	55069
HPRD ID		17979	08541
Ensembl ID		ENSG00000182631	ENSG00000106609
Uniprot IDs		Q9NSD7	Q9NWD8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Toll-like Receptor Signaling Pathway Cellular Response To Manganese Ion Response To Manganese Ion Cellular Response To Catecholamine Stimulus Response To Catecholamine Low-density Lipoprotein Particle Receptor Binding Midbody Positive Regulation Of ATP Metabolic Process Regulation Of System Process Protein Phosphatase Inhibitor Activity Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Regulation Of Multicellular Organism Growth Acetylcholine Receptor Activator Activity Regulation Of Defense Response Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process G Protein-coupled Receptor Binding Protein Heterodimerization Activity Lipoprotein Particle Positive Regulation Of Protein Import Mu-type Opioid Receptor Binding Actin Rod Assembly Regulation Of Heart Rate By Hormone ATPase Regulator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Immune Response Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Protein Transport Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Protein Phosphatase Binding Melanosome Trans-Golgi Network Membrane Regulation Of Innate Immune Response Positive Regulation Of Cellular Component Organization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway	Membrane Establishment Of Protein Localization To Membrane Schmidt-Lanterman Incisure Structural Constituent Of Myelin Sheath
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