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CDK17 and PRKACG
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
CDK17
PRKACG
Gene Name
cyclin-dependent kinase 17
protein kinase, cAMP-dependent, catalytic, gamma
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Ciliary Base
Molecular Function
Protein Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
CAMP-dependent Protein Kinase Activity
ATP Binding
Biological Process
Protein Phosphorylation
Regulation Of Cell Cycle
Renal Water Homeostasis
Carbohydrate Metabolic Process
Glucose Metabolic Process
Gluconeogenesis
Energy Reserve Metabolic Process
Protein Phosphorylation
Water Transport
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Activation Of Phospholipase C Activity
Spermatogenesis
Blood Coagulation
Fibroblast Growth Factor Receptor Signaling Pathway
Male Gonad Development
Pathogenesis
Triglyceride Catabolic Process
Activation Of Protein Kinase A Activity
Intracellular Signal Transduction
Small Molecule Metabolic Process
Innate Immune Response
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Insulin Secretion
Transmembrane Transport
Cellular Response To Glucagon Stimulus
Pathways
Signaling by GPCR
Ca-dependent events
CaM pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Metabolism of lipids and lipoproteins
Integration of energy metabolism
Hedgehog 'off' state
Phospholipase C-mediated cascade
Signaling by FGFR in disease
Signaling by EGFRvIII in Cancer
PLCG1 events in ERBB2 signaling
Gluconeogenesis
Glucose metabolism
DAP12 signaling
Rap1 signalling
Myoclonic epilepsy of Lafora
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
Glycogen storage diseases
PKA-mediated phosphorylation of key metabolic factors
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Glucagon signaling in metabolic regulation
Signaling by PDGF
Calmodulin induced events
DAP12 interactions
PKA-mediated phosphorylation of CREB
Opioid Signalling
PKA activation
Aquaporin-mediated transport
Factors involved in megakaryocyte development and platelet production
CREB phosphorylation through the activation of Adenylate Cyclase
EGFR interacts with phospholipase C-gamma
Signaling by ERBB2
Signaling by EGFR
PKA-mediated phosphorylation of CREB
Signaling by VEGF
Downstream signal transduction
Calmodulin induced events
Signaling by EGFR in Cancer
PKA activation
Metabolism of carbohydrates
Transmission across Chemical Synapses
Adaptive Immune System
VEGFA-VEGFR2 Pathway
DAG and IP3 signaling
CaM pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events
Downstream signaling of activated FGFR
DARPP-32 events
Post NMDA receptor activation events
Innate Immune System
PKA activation in glucagon signalling
Signalling by NGF
PLC beta mediated events
Vasopressin regulates renal water homeostasis via Aquaporins
Regulation of insulin secretion
Signaling by Ligand-Responsive EGFR Variants in Cancer
Lipid digestion, mobilization, and transport
NGF signalling via TRKA from the plasma membrane
G-protein mediated events
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by FGFR
PLC-gamma1 signalling
Signaling by Hedgehog
Degradation of GLI1 by the proteasome
GLI3 is processed to GLI3R by the proteasome
Degradation of GLI2 by the proteasome
Drugs
Diseases
GWAS
Phospholipid levels (plasma) (
22359512
)
Protein-Protein Interactions
8 interactors:
APP
EPHA2
PRKACG
TDRD7
TGFBR1
YWHAG
YWHAQ
YWHAZ
5 interactors:
CDK17
CETP
HMGN1
TNP1
TNP2
Entrez ID
5128
5568
HPRD ID
09141
01483
Ensembl ID
ENSG00000059758
ENSG00000165059
Uniprot IDs
Q00537
P22612
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Establishment Of Protein Localization
Regulation Of Protein Localization
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Apoptotic Process
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Programmed Cell Death
Regulation Of Cellular Localization
Cell Death
Death
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Intracellular Transport
Positive Regulation Of Mitochondrion Organization
Apoptotic Signaling Pathway
Regulation Of Mitochondrion Organization
Lens Development In Camera-type Eye
Regulation Of Signaling
Intracellular Signal Transduction
Regulation Of Intracellular Transport
Regulation Of Phosphorylation
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Wound Healing
Positive Regulation Of Cell Death
System Development
Lens Morphogenesis In Camera-type Eye
Regulation Of Phosphorus Metabolic Process
Response To Wounding
Lens Fiber Cell Differentiation
Positive Regulation Of Transport
Regulation Of Protein Kinase Activity
Regulation Of Signal Transduction
Regulation Of Kinase Activity
Sexual Reproduction
Multicellular Organismal Development
Organ Development
Anatomical Structure Development
Phosphorylation
Regulation Of Cellular Component Organization
Signal Transduction
Camera-type Eye Development
Reproduction
Developmental Process
Regulation Of Protein Phosphorylation
Eye Development
Positive Regulation Of Organelle Organization
Signaling
Immune System Process
Protein Targeting
Sperm Motility
Fertilization, Exchange Of Chromosomal Proteins
Single Fertilization
Male Pronucleus Assembly
Fertilization
Triglyceride Transport
Post-embryonic Camera-type Eye Morphogenesis
Pyrimidine Dimer Repair By Nucleotide-excision Repair
Penetration Of Zona Pellucida
Post-embryonic Organ Morphogenesis
Very-low-density Lipoprotein Particle Remodeling
Phospholipid Homeostasis
Post-embryonic Camera-type Eye Development
Triglyceride-rich Lipoprotein Particle Remodeling
Spermatid Nucleus Elongation
Low-density Lipoprotein Particle Remodeling
Response To UV-C
Pyrimidine Dimer Repair
Nucleosome Disassembly
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
High-density Lipoprotein Particle Remodeling
Response To UV-B
Reverse Cholesterol Transport
Spermatogenesis
Regulation Of Development, Heterochronic
Male Gamete Generation
Single Strand Break Repair
Regulation Of Cholesterol Efflux
Plasma Lipoprotein Particle Remodeling
Acrosome Reaction
DNA Repair
Positive Regulation Of DNA-templated Transcription, Elongation
Spermatid Nucleus Differentiation
Gamete Generation
Histone Exchange
Chromatin Silencing
Triglyceride Homeostasis
Acylglycerol Homeostasis
Regulation Of Cholesterol Transport
Chromatin Organization
Transcription-coupled Nucleotide-excision Repair
Binding Of Sperm To Zona Pellucida
Regulation Of Macrophage Derived Foam Cell Differentiation
Calcium Ion-dependent Exocytosis
Anion Homeostasis
Sexual Reproduction
Multicellular Organismal Reproductive Process
Sperm-egg Recognition
Regulation Of DNA-templated Transcription, Elongation
Phosphatidylcholine Metabolic Process
Tagcloud
?
agouti
albinism
asip
atf1
delta25
dopachrome
edn1
edn3
ednrb
exoc2
exocyst
kitlg
ludwigshafen
mc1r
microphthalmia
oca2
oculocutaneous
pigmentation
prkar1a
prkar2a
prkar2b
proopiomelanocortin
slc24a4
slc45a2
tautomerase
tpcn2
tubb3
tyrp1
Tagcloud (Difference)
?
agouti
albinism
asip
atf1
delta25
dopachrome
edn1
edn3
ednrb
exoc2
exocyst
kitlg
ludwigshafen
mc1r
microphthalmia
oca2
oculocutaneous
pigmentation
prkar1a
prkar2a
prkar2b
proopiomelanocortin
slc24a4
slc45a2
tautomerase
tpcn2
tubb3
tyrp1
Tagcloud (Intersection)
?