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SERPINA10 and PIAS3
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
SERPINA10
PIAS3
Gene Name
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
protein inhibitor of activated STAT, 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Dendrite
Synapse
Molecular Function
Serine-type Endopeptidase Inhibitor Activity
Heparin Binding
Protein Binding
Protein C-terminus Binding
Zinc Ion Binding
Potassium Channel Regulator Activity
Ligase Activity
SUMO Transferase Activity
Enzyme Binding
Protein N-terminus Binding
Biological Process
Blood Coagulation
Negative Regulation Of Endopeptidase Activity
Regulation Of Acrosome Reaction
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Response To Hormone
Positive Regulation Of Gene Expression
Protein Sumoylation
Positive Regulation Of Protein Sumoylation
Positive Regulation Of Membrane Potential
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
F10
PIAS3
PSMB7
49 interactors:
AR
ATF7IP
C19orf60
CARHSP1
CBS
CREM
EP300
ESR1
ESR2
GEMIN4
GFI1
GLUL
HABP4
HDAC1
HMGA2
MITF
NCOA2
NR3C2
OPN1LW
PGR
PPP1CA
PRPF40A
PSMC1
RAC1
RELA
SATB1
SERBP1
SERPINA10
SIAH1
SIAH2
SKIL
SMAD2
SMAD3
SMAD4
SREBF2
STAT3
SUMO1
SUMO2
SUMO3
TBP
TRIM27
TRIM32
TRIM55
TRIM63
UBA1
UBE2I
ZFHX3
ZMIZ1
ZMIZ2
Entrez ID
51156
10401
HPRD ID
09245
09068
Ensembl ID
ENSG00000140093
ENSG00000131788
Uniprot IDs
Q9UK55
B3KNI3
Q6IAR4
Q9Y6X2
PDB IDs
3F1S
3H5C
4AFX
4AJU
Enriched GO Terms of Interacting Partners
?
Blood Coagulation, Extrinsic Pathway
Positive Regulation Of Protein Sumoylation
Peptidyl-glutamic Acid Carboxylation
Blood Coagulation, Intrinsic Pathway
Protein Modification By Small Protein Conjugation
Regulation Of Protein Sumoylation
Cellular Protein Modification Process
Protein Sumoylation
Positive Regulation Of Protein Modification Process
Peptidyl-amino Acid Modification
Positive Regulation Of Membrane Potential
Cellular Protein Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Positive Regulation Of Protein Metabolic Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Signal Transduction
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Kinase B Signaling
DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Signal Transduction In Response To DNA Damage
Proteolysis
Mitotic DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Mitotic DNA Integrity Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Protein Ubiquitination
Protein Metabolic Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Signal Transduction By P53 Class Mediator
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Positive Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Metabolic Process
Gene Expression
Transcription Initiation From RNA Polymerase II Promoter
RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
DNA-templated Transcription, Initiation
Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Response To Organic Substance
Regulation Of Cellular Process
Macromolecule Biosynthetic Process
Positive Regulation Of Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Viral Process
Cellular Response To Organic Substance
Biosynthetic Process
Epithelium Development
Regulation Of Signal Transduction
Regulation Of Cell Death
Regulation Of Signaling
Response To Stimulus
Cellular Response To Stimulus
Tagcloud
?
achieved
atm
atr
consistently
crucial
dbc1
deficient
diverse
establish
etoposide
finely
genotoxic
interaction
knockdown
metabolism
modification
modifier
promoted
promotion
remarkably
senp1
sirt1
sumo
sumo1
sumo2
sumoylation
switching
transactivation
ubiquitin
Tagcloud (Difference)
?
achieved
atm
atr
consistently
crucial
dbc1
deficient
diverse
establish
etoposide
finely
genotoxic
interaction
knockdown
metabolism
modification
modifier
promoted
promotion
remarkably
senp1
sirt1
sumo
sumo1
sumo2
sumoylation
switching
transactivation
ubiquitin
Tagcloud (Intersection)
?