DESI2 and PLIN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DESI2	PLIN2
Description		desumoylating isopeptidase 2	perilipin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Plasma Membrane Membrane
	Molecular Function	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity Long-chain Fatty Acyl-CoA Hydrolase Activity K63-linked Deubiquitinase Activity Deubiquitinase Activity K48-linked Deubiquitinase Activity	Protein Binding
	Biological Process	Proteolysis Macromolecule Depalmitoylation	Response To Xenobiotic Stimulus Positive Regulation Of Triglyceride Storage Long-chain Fatty Acid Transport Lipid Storage Cellular Response To Glucose Starvation Lipid Droplet Disassembly
Pathways			PPARA activates gene expression Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS			Abdominal aortic calcification levels ( 31659325) Systolic blood pressure ( 30578418)
Interacting Genes		11 interacting genes: ARFIP1 BNIP2 COQ8A MYG1 NFU1 PBX3 PLIN2 SEMA3G SH3GLB1 SPART THAP7	9 interacting genes: ABHD5 ARF1 DESI2 HTATIP2 MAPK10 OGT POGZ SFT2D2 UBR1
Entrez ID		51029	123
HPRD ID		15153	00057
Ensembl ID		ENSG00000121644	ENSG00000147872
Uniprot IDs		Q9BSY9	Q6FHZ7 Q99541
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipid Droplet Lipid Droplet Organization Cellular Response To Glucose Starvation Posterior Compartment Specification Anterior Compartment Pattern Formation Midbody Negative Regulation Of Collateral Sprouting In Absence Of Injury Negative Regulation Of Axonogenesis Negative Regulation Of Retrograde Transport, Endosome To Golgi Protein Localization To Vacuolar Membrane
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