DESI2 and SEMA3G

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DESI2	SEMA3G
Description		desumoylating isopeptidase 2	semaphorin 3G
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Extracellular Region Plasma Membrane Extracellular Exosome
	Molecular Function	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity Long-chain Fatty Acyl-CoA Hydrolase Activity K63-linked Deubiquitinase Activity Deubiquitinase Activity K48-linked Deubiquitinase Activity	Signaling Receptor Binding Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity
	Biological Process	Proteolysis Macromolecule Depalmitoylation	Neural Crest Cell Migration Axon Guidance Positive Regulation Of Cell Migration Negative Regulation Of Axon Extension Forebrain Development Negative Chemotaxis Semaphorin-plexin Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Blood protein levels ( 30072576) Schizophrenia ( 23974872) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		11 interacting genes: ARFIP1 BNIP2 COQ8A MYG1 NFU1 PBX3 PLIN2 SEMA3G SH3GLB1 SPART THAP7	2 interacting genes: DESI2 RHOU
Entrez ID		51029	56920
HPRD ID		15153	14251
Ensembl ID		ENSG00000121644	ENSG00000010319
Uniprot IDs		Q9BSY9	Q9NS98
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipid Droplet Lipid Droplet Organization Cellular Response To Glucose Starvation Posterior Compartment Specification Anterior Compartment Pattern Formation Midbody Negative Regulation Of Collateral Sprouting In Absence Of Injury Negative Regulation Of Axonogenesis Negative Regulation Of Retrograde Transport, Endosome To Golgi Protein Localization To Vacuolar Membrane	Macromolecule Depalmitoylation Palmitoyl-(protein) Hydrolase Activity Long-chain Fatty Acyl-CoA Hydrolase Activity K63-linked Deubiquitinase Activity K48-linked Deubiquitinase Activity Positive Regulation Of Focal Adhesion Disassembly Macromolecule Deacylation Deubiquitinase Activity Rac Protein Signal Transduction Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Positive Regulation Of Protein Targeting To Mitochondrion Podosome Regulation Of Protein Targeting To Mitochondrion Cysteine-type Deubiquitinase Activity Regulation Of Cell-substrate Junction Organization Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Establishment Of Cell Polarity
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