OVGP1 and ASL

Number of citations: 38 (PubMedID 21988832)
Data Source: BioGRID (two hybrid)

		OVGP1	ASL
Name		oviductal glycoprotein 1	argininosuccinate lyase
Structure		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Microtubule Cytoskeleton Transport Vesicle Cytoplasmic Vesicle Egg Coat Perivitelline Space	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Chitinase Activity Chitin Binding	Catalytic Activity Argininosuccinate Lyase Activity Protein Binding Lyase Activity Identical Protein Binding
	Biological Process	Carbohydrate Metabolic Process Chitin Catabolic Process Single Fertilization Female Pregnancy Negative Regulation Of Binding Of Sperm To Zona Pellucida	Urea Cycle Amino Acid Metabolic Process Arginine Metabolic Process L-arginine Biosynthetic Process Locomotory Behavior Amino Acid Biosynthetic Process Post-embryonic Development Ammonia Assimilation Cycle L-arginine Biosynthetic Process Via Ornithine Positive Regulation Of Nitric Oxide Biosynthetic Process L-amino Acid Metabolic Process
Pathways		Interaction With Cumulus Cells And The Zona Pellucida	Urea cycle
Drugs		None	Arginine Argininosuccinate 2-(N-morpholino)ethanesulfonic acid
Diseases		None	Argininosuccinic aciduria (ARGINSA); Argininosuccinate lyase deficiency
GWAS		Response to antidepressants (symptom improvement) ( 29160301 )	No GWAS studies recorded
Interacting Genes		4 interacting genes: ASL MYH9 RASA4 STATH	10 interacting genes: CLK1 CSNK2A2 FBP1 HMOX1 MCMBP NTAQ1 OVGP1 QARS1 SRPK2 TRIM3
Entrez ID		5016	435
HPRD ID		04658	01948
Ensembl ID		ENSG00000085465	ENSG00000126522
Uniprot IDs		Q12889 Q86YN0	A0A024RDL8 A0A0S2Z316 P04424
PDB IDs		Not available	1AOS 1K62
GO Terms Enriched among Interactors		L-arginine Biosynthetic Process Via Ornithine Argininosuccinate Lyase Activity Amino Acid Biosynthetic Process Nitrogen Utilization Ammonia Assimilation Cycle Uracil Binding Beta-alanine Metabolic Process Thymidine Catabolic Process Uracil Catabolic Process Beta-alanine Biosynthetic Process Dihydropyrimidine Dehydrogenase (NADP+) Activity Uropod Organization Cortical Granule Exocytosis Negative Regulation Of Actin Filament Severing Positive Regulation Of Protein Processing In Phagocytic Vesicle Extracellular Matrix Constituent, Lubricant Activity Pyrimidine Nucleoside Catabolic Process Thymine Metabolic Process Thymine Catabolic Process Purine Nucleobase Catabolic Process Myosin II Filament L-arginine Biosynthetic Process CMP Catabolic Process DUMP Catabolic Process Actomyosin Contractile Ring Structural Constituent Of Tooth Enamel Hydroxyapatite Binding DCMP Catabolic Process UMP Catabolic Process Cortical Granule Cytoplasmic Actin-based Contraction Involved In Cell Motility Deoxyribonucleoside Catabolic Process Saliva Secretion Amino Acid Metabolic Process Carboxylic Acid Biosynthetic Process Thymidine Metabolic Process Pyrimidine Nucleobase Catabolic Process Pyrimidine Ribonucleotide Catabolic Process Regulation Of Plasma Membrane Repair Establishment Of Meiotic Spindle Localization Establishment Of T Cell Polarity Actomyosin Supramolecular Fiber Urea Cycle Urea Metabolic Process Nitrogen Cycle Metabolic Process Pyrimidine Nucleoside Metabolic Process Nucleobase-containing Small Molecule Catabolic Process Deoxyribonucleoside Monophosphate Catabolic Process Uropod	Protein Serine Kinase Activity Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Catabolic Process Phosphoric Ester Hydrolase Activity Cellular Response To Raffinose Fructose 1,6-bisphosphate 1-phosphatase Activity Heme Oxidation Smooth Muscle Hyperplasia Heme Oxygenase (decyclizing) Activity Wound Healing Involved In Inflammatory Response Perivitelline Space Glutamine-tRNA Ligase Activity Glutaminyl-tRNA Aminoacylation Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity Regulation Of Apoptotic Signaling Pathway Protein Serine/threonine Kinase Activity Protein Kinase CK2 Complex Cellular Hypotonic Salinity Response Cytosol Cellular Response To Cisplatin Negative Regulation Of Binding Of Sperm To Zona Pellucida Egg Coat Nuclear Speck Organization