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SIX6 and GTF2A1L
Number of citations of the paper that reports this interaction (PMID
20211142
)
148
Data Source:
BioGRID
(two hybrid)
SIX6
GTF2A1L
Gene Name
SIX homeobox 6
general transcription factor IIA, 1-like
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Transcription Factor TFIIA Complex
Cytoplasm
Molecular Function
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
DNA Binding
DNA Binding
Transcription Coactivator Activity
Biological Process
Visual Perception
Organ Morphogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Cognition
Pathways
Drugs
Diseases
GWAS
Glaucoma (primary open-angle) (
22419738
22570617
)
Height (
20881960
)
Refractive error (
23396134
)
Polycystic ovary syndrome (
21151128
)
Protein-Protein Interactions
3 interactors:
AES
GTF2A1L
TLE1
25 interactors:
ASCL3
ATF4
CEBPE
CSNK2A1
CSNK2A2
EMX1
EMX2
GAB1
GTF2A2
HMG20A
HOXA5
HOXC11
HOXC9
ID3
MAFF
MAFG
NKX2-3
PAX9
RBFOX2
SIX6
SUB1
TBP
TLX2
TLX3
ZBTB3
Entrez ID
4990
11036
HPRD ID
07557
05640
Ensembl ID
ENSG00000242441
Uniprot IDs
O95475
Q6P051
Q9UNN4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Anoikis
Negative Regulation Of Wnt Signaling Pathway
Wnt Signaling Pathway
Positive Regulation Of Anoikis
Regulation Of Wnt Signaling Pathway
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Anoikis
RNA Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Response To Cytokine Stimulus
Organ Morphogenesis
Regulation Of Transcription, DNA-templated
Negative Regulation Of Signal Transduction
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Protein Binding
Negative Regulation Of Signaling
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Response To Interleukin-1
Regulation Of Apoptotic Process
Regulation Of Cell Death
Negative Regulation Of Binding
Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Notch Signaling Pathway
Regulation Of Protein Binding
Negative Regulation Of Canonical Wnt Signaling Pathway
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Extracellular Stimulus
DNA-templated Transcription, Initiation
Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
RNA Metabolic Process
Gene Expression
Regulation Of Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Multicellular Organismal Development
System Development
Anatomical Structure Development
Transcription From RNA Polymerase II Promoter
Developmental Process
Regulation Of Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Embryo Development
Cell Differentiation
Positive Regulation Of Gene Expression
Anatomical Structure Morphogenesis
Organ Development
Positive Regulation Of Cellular Biosynthetic Process
Cellular Metabolic Process
Organ Morphogenesis
Chordate Embryonic Development
Embryo Development Ending In Birth Or Egg Hatching
Generation Of Neurons
Positive Regulation Of Cellular Metabolic Process
Neurogenesis
Cerebral Cortex Regionalization
Positive Regulation Of Metabolic Process
Neuron Differentiation
Telencephalon Regionalization
Pattern Specification Process
Regulation Of Cell Differentiation
Embryonic Organ Development
Anterior/posterior Pattern Specification
Tagcloud
?
as1
atoh7
beadchip
cav1
cav2
cdkn2b
cnvs
cyp1b1
duplications
fndc3b
galc
gas7
glaugen
human660w
interrogated
kilobases
lrp12
merit
myoc
neighbor
optn
penncnv
poag
quad
six1
srbd1
tmco1
wdr36
zfpm2
Tagcloud (Difference)
?
as1
atoh7
beadchip
cav1
cav2
cdkn2b
cnvs
cyp1b1
duplications
fndc3b
galc
gas7
glaugen
human660w
interrogated
kilobases
lrp12
merit
myoc
neighbor
optn
penncnv
poag
quad
six1
srbd1
tmco1
wdr36
zfpm2
Tagcloud (Intersection)
?