SIX6

Gene Name		SIX homeobox 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding
	Biological Process	Visual Perception Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Glaucoma (primary open-angle) ( 22419738 22570617) Height ( 20881960) Refractive error ( 23396134)
Protein-protein Interactions		3 interactors: AES GTF2A1L TLE1
Entrez ID		4990
HPRD ID		07557
Ensembl ID
Uniprot IDs		O95475 Q6P051
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Anoikis Negative Regulation Of Wnt Signaling Pathway Wnt Signaling Pathway Positive Regulation Of Anoikis Regulation Of Wnt Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Anoikis RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Response To Cytokine Stimulus Organ Morphogenesis Regulation Of Transcription, DNA-templated Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Protein Binding Negative Regulation Of Signaling Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Response To Interleukin-1 Regulation Of Apoptotic Process Regulation Of Cell Death Negative Regulation Of Binding Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Notch Signaling Pathway Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Cellular Response To Extracellular Stimulus DNA-templated Transcription, Initiation Regulation Of Canonical Wnt Signaling Pathway
Tagcloud ?		as1 atoh7 beadchip cav1 cav2 cdkn2b cnvs cyp1b1 duplications fndc3b galc gas7 glaugen human660w interrogated kilobases lrp12 merit myoc neighbor optn penncnv poag quad six1 srbd1 tmco1 wdr36 zfpm2