ODC1 and SSR1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ODC1	SSR1
Gene Name		ornithine decarboxylase 1	signal sequence receptor, alpha
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Ornithine Decarboxylase Activity Protein Homodimerization Activity	Protein Binding
	Biological Process	Kidney Development Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Positive Regulation Of Cell Proliferation Response To Virus Putrescine Biosynthetic Process From Ornithine Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Catabolic Process Small Molecule Metabolic Process	Translation Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Cell Proliferation Gene Expression Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines Metabolism of amino acids and derivatives	IRE1alpha activates chaperones Translation SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs		Pyridoxal Phosphate Spermine Putrescine Pyridoxine-5\'-Phosphate N-Pyridoxyl-Glycine-5-Monophosphate Alpha-Difluoromethylornithine N\'-Pyridoxyl-Lysine-5\'-Monophosphate G418
Diseases
GWAS
Protein-Protein Interactions		9 interactors: AZI2 CSNK2B GORASP2 KAT5 OAZ1 OAZ2 OAZ3 SSR1 TK1	8 interactors: DKC1 EEF1A1 HSPA13 NUP54 ODC1 PTN SERPINF2 UTP14A
Entrez ID		4953	6745
HPRD ID		01324	02924
Ensembl ID		ENSG00000115758	ENSG00000124783
Uniprot IDs		P11926	E9PAL7 P43307
PDB IDs		1D7K 2ON3 2OO0
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Polyamine Transmembrane Transport Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Negative Regulation Of Transmembrane Transport Positive Regulation Of Protein Metabolic Process Cellular Biogenic Amine Metabolic Process Amine Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Transport Regulation Of Cellular Amino Acid Metabolic Process Tumor Necrosis Factor Production Fetal Process Involved In Parturition Positive Regulation Of Metabolic Process Regulation Of Cellular Ketone Metabolic Process Skeletal Muscle Cell Proliferation Putrescine Transport Regulation Of Catalytic Activity Interferon-alpha Production Interleukin-6 Production Positive Regulation Of Intracellular Protein Transport Dendritic Cell Proliferation Response To Cortisol Thymidine Metabolic Process Mitotic Cell Cycle Negative Regulation Of Catalytic Activity Positive Regulation Of Activin Receptor Signaling Pathway Deoxyribonucleoside Monophosphate Biosynthetic Process Adiponectin-activated Signaling Pathway Biosynthetic Process Positive Regulation Of Intracellular Transport Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Positive Regulation Of Protein Modification Process Regulation Of Intracellular Protein Transport Endothelial Tube Morphogenesis Response To Hormone DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Type I Interferon Production Positive Regulation Of Protein Transport Positive Regulation Of Cellular Protein Metabolic Process Parturition Interferon-gamma Production Cellular Response To Estradiol Stimulus Negative Regulation Of Blood Vessel Endothelial Cell Migration Small Molecule Metabolic Process Negative Regulation Of Interleukin-2 Production	Putrescine Biosynthetic Process From Ornithine RRNA Processing RRNA Metabolic Process Putrescine Biosynthetic Process Regulation Of Blood Vessel Size By Renin-angiotensin Ribosome Biogenesis Positive Regulation Of Cell Proliferation Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Ornithine Metabolic Process Negative Regulation Of Plasminogen Activation Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Negative Regulation Of Fibrinolysis
Tagcloud ?		abd antagonistic consequent derepression elevate esc h3k27 h3k27me3 heterozygous lived longevity methyltransferase modifying mutants organismal partner pcg perturbation phenotypes polycomb prc2 repressive silencing starvation trimethylated trithorax trx trxg z	3t3 a4 adipocytes antioxidants cyclic cytoprotection dismutase endoplasmic ern1 fabp4 glutathione gmp gsh gsta4 h2o2 kinds l1 lowering nitro orm1 ormdl3 peroxide reticulum scavenger sod spliced superoxide transferase xbp1s
Tagcloud (Difference) ?		abd antagonistic consequent derepression elevate esc h3k27 h3k27me3 heterozygous lived longevity methyltransferase modifying mutants organismal partner pcg perturbation phenotypes polycomb prc2 repressive silencing starvation trimethylated trithorax trx trxg z	3t3 a4 adipocytes antioxidants cyclic cytoprotection dismutase endoplasmic ern1 fabp4 glutathione gmp gsh gsta4 h2o2 kinds l1 lowering nitro orm1 ormdl3 peroxide reticulum scavenger sod spliced superoxide transferase xbp1s
Tagcloud (Intersection) ?