ODC1 and OAZ2

Number of citations of the paper that reports this interaction (PubMedID 12359729)
0

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		ODC1	OAZ2
Description		ornithine decarboxylase 1	ornithine decarboxylase antizyme 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	Catalytic Activity Ornithine Decarboxylase Activity Protein Binding Lyase Activity Carboxy-lyase Activity Protein Homodimerization Activity	Protein Binding Ornithine Decarboxylase Inhibitor Activity
	Biological Process	Kidney Development Polyamine Metabolic Process Polyamine Biosynthetic Process Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Response To Virus Putrescine Biosynthetic Process From Arginine, Via Ornithine Regulation Of Protein Catabolic Process	Biogenic Amine Metabolic Process Polyamine Metabolic Process Polyamine Biosynthetic Process Positive Regulation Of Protein Catabolic Process Viral Translational Frameshifting Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines
Drugs		Pyridoxal phosphate Spermine Sildenafil Valproic acid Putrescine Pyridoxine phosphate N-Pyridoxyl-Glycine-5-Monophosphate L-Eflornithine N(6)-(pyridoxal phosphate)-L-lysine Geneticin Eflornithine
Diseases
GWAS			Aluminium levels ( 26025379) Neuroticism ( 29255261)
Interacting Genes		17 interacting genes: BAAT CSNK2B GORASP2 HEMGN KAT5 MAP2K1 NANS OAZ1 OAZ2 RSC1A1 SSR1 STX17 TDRD7 TK1 TMOD1 TSTD2 ZNF510	5 interacting genes: BDKRB1 CDR2 OAZ1 ODC1 SYTL3
Entrez ID		4953	4947
HPRD ID		01324	11966
Ensembl ID		ENSG00000115758	ENSG00000180304
Uniprot IDs		B4DXF8 P11926	O95190
PDB IDs		1D7K 2ON3 2OO0 4ZGY 5BWA 7S3F 7S3G 7U6P 7U6U 9B8M 9B8N
Enriched GO Terms of Interacting Partners?		Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Viral Translational Frameshifting Polyamine Biosynthetic Process Polyamine Metabolic Process Negative Regulation Of Transmembrane Transport Golgi Organization Viral Process Amine Biosynthetic Process Biogenic Amine Biosynthetic Process	Polyamine Biosynthetic Process Polyamine Metabolic Process Amine Biosynthetic Process Biogenic Amine Biosynthetic Process Biogenic Amine Metabolic Process Amine Metabolic Process Bradykinin Receptor Activity Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Ornithine Decarboxylase Activity Putrescine Biosynthetic Process From Arginine, Via Ornithine Signal Peptidase Complex Putrescine Biosynthetic Process Viral Translational Frameshifting Putrescine Metabolic Process Signal Peptide Processing Neurexin Family Protein Binding
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