ODC1 and OAZ2

Number of citations of the paper that reports this interaction (PMID 12359729)
13

Data Source:
HPRD (in vitro)

		ODC1	OAZ2
Gene Name		ornithine decarboxylase 1	ornithine decarboxylase antizyme 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol	Nucleus Cytosol
	Molecular Function	Ornithine Decarboxylase Activity Protein Homodimerization Activity	Protein Binding Ornithine Decarboxylase Inhibitor Activity
	Biological Process	Kidney Development Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Positive Regulation Of Cell Proliferation Response To Virus Putrescine Biosynthetic Process From Ornithine Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Catabolic Process Small Molecule Metabolic Process	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Polyamine Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Catalytic Activity Small Molecule Metabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines Metabolism of amino acids and derivatives	Regulation of ornithine decarboxylase (ODC) Metabolism of amino acids and derivatives
Drugs		Pyridoxal Phosphate Spermine Putrescine Pyridoxine-5\'-Phosphate N-Pyridoxyl-Glycine-5-Monophosphate Alpha-Difluoromethylornithine N\'-Pyridoxyl-Lysine-5\'-Monophosphate G418
Diseases
GWAS
Protein-Protein Interactions		9 interactors: AZI2 CSNK2B GORASP2 KAT5 OAZ1 OAZ2 OAZ3 SSR1 TK1	2 interactors: OAZ1 ODC1
Entrez ID		4953	4947
HPRD ID		01324	11966
Ensembl ID		ENSG00000115758	ENSG00000180304
Uniprot IDs		P11926	O95190
PDB IDs		1D7K 2ON3 2OO0
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Polyamine Transmembrane Transport Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Negative Regulation Of Transmembrane Transport Positive Regulation Of Protein Metabolic Process Cellular Biogenic Amine Metabolic Process Amine Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Transport Regulation Of Cellular Amino Acid Metabolic Process Tumor Necrosis Factor Production Fetal Process Involved In Parturition Positive Regulation Of Metabolic Process Regulation Of Cellular Ketone Metabolic Process Skeletal Muscle Cell Proliferation Putrescine Transport Regulation Of Catalytic Activity Interferon-alpha Production Interleukin-6 Production Positive Regulation Of Intracellular Protein Transport Dendritic Cell Proliferation Response To Cortisol Thymidine Metabolic Process Mitotic Cell Cycle Negative Regulation Of Catalytic Activity Positive Regulation Of Activin Receptor Signaling Pathway Deoxyribonucleoside Monophosphate Biosynthetic Process Adiponectin-activated Signaling Pathway Biosynthetic Process Positive Regulation Of Intracellular Transport Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Positive Regulation Of Protein Modification Process Regulation Of Intracellular Protein Transport Endothelial Tube Morphogenesis Response To Hormone DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Type I Interferon Production Positive Regulation Of Protein Transport Positive Regulation Of Cellular Protein Metabolic Process Parturition Interferon-gamma Production Cellular Response To Estradiol Stimulus Negative Regulation Of Blood Vessel Endothelial Cell Migration Small Molecule Metabolic Process Negative Regulation Of Interleukin-2 Production	Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Cellular Biogenic Amine Metabolic Process Amine Metabolic Process Putrescine Biosynthetic Process From Ornithine Putrescine Biosynthetic Process Regulation Of Protein Catabolic Process Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Polyamine Transmembrane Transport Regulation Of Cellular Ketone Metabolic Process Ornithine Metabolic Process Negative Regulation Of Transmembrane Transport Regulation Of Protein Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Intracellular Protein Transport
Tagcloud ?		abd antagonistic consequent derepression elevate esc h3k27 h3k27me3 heterozygous lived longevity methyltransferase modifying mutants organismal partner pcg perturbation phenotypes polycomb prc2 repressive silencing starvation trimethylated trithorax trx trxg z
Tagcloud (Difference) ?		abd antagonistic consequent derepression elevate esc h3k27 h3k27me3 heterozygous lived longevity methyltransferase modifying mutants organismal partner pcg perturbation phenotypes polycomb prc2 repressive silencing starvation trimethylated trithorax trx trxg z
Tagcloud (Intersection) ?