ODC1 and TSTD2

Number of citations of the paper that reports this interaction (PubMedID 24412244)
0

Data Source:
BioGRID (two hybrid)

		ODC1	TSTD2
Description		ornithine decarboxylase 1	thiosulfate sulfurtransferase like domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Catalytic Activity Ornithine Decarboxylase Activity Protein Binding Lyase Activity Carboxy-lyase Activity Protein Homodimerization Activity	Protein Binding
	Biological Process	Kidney Development Polyamine Metabolic Process Polyamine Biosynthetic Process Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Response To Virus Putrescine Biosynthetic Process From Arginine, Via Ornithine Regulation Of Protein Catabolic Process
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines
Drugs		Pyridoxal phosphate Spermine Sildenafil Valproic acid Putrescine Pyridoxine phosphate N-Pyridoxyl-Glycine-5-Monophosphate L-Eflornithine N(6)-(pyridoxal phosphate)-L-lysine Geneticin Eflornithine
Diseases
GWAS
Interacting Genes		17 interacting genes: BAAT CSNK2B GORASP2 HEMGN KAT5 MAP2K1 NANS OAZ1 OAZ2 RSC1A1 SSR1 STX17 TDRD7 TK1 TMOD1 TSTD2 ZNF510	33 interacting genes: AGR2 APC AURKA BLZF1 BUB1 CCND1 DCC EGFR FLCN IKZF1 IKZF3 INCA1 ISY1-RAB43 L3MBTL3 LHX4 MCC MEOX2 MLH3 MUTYH ODC1 PICK1 PTPRJ REL SMAD4 SSX2IP TCF4 TOX3 VPS52 ZBTB14 ZFPL1 ZNF438 ZNF774 ZRANB1
Entrez ID		4953	158427
HPRD ID		01324	16679
Ensembl ID		ENSG00000115758	ENSG00000136925
Uniprot IDs		B4DXF8 P11926	Q5T7W7
PDB IDs		1D7K 2ON3 2OO0 4ZGY 5BWA 7S3F 7S3G 7U6P 7U6U 9B8M 9B8N
Enriched GO Terms of Interacting Partners?		Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Viral Translational Frameshifting Polyamine Biosynthetic Process Polyamine Metabolic Process Negative Regulation Of Transmembrane Transport Golgi Organization Viral Process Amine Biosynthetic Process Biogenic Amine Biosynthetic Process	Nucleus Nucleoplasm Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Regulation Of Programmed Cell Death Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA Binding Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mesoderm Development DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Cyclin-dependent Protein Kinase Activity Regulation Of Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Phosphate Metabolic Process Gamma-catenin Binding Response To UV-A Regulation Of RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cardiocyte Differentiation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Component Organization Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Kinase Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of ERBB Signaling Pathway RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Kinase Activity Cellular Developmental Process Protein-containing Complex Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Catabolic Process Developmental Process Digestive Tract Morphogenesis Regulation Of Cell Population Proliferation Negative Regulation Of Protein Metabolic Process Neuron Projection Guidance Axon Guidance Ruffle Membrane Heart Valve Development Beta-catenin Binding Animal Organ Development Negative Regulation Of Protein Phosphorylation Negative Regulation Of Metabolic Process
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