OAT and NUDT3

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		OAT	NUDT3
Gene Name		ornithine aminotransferase	nudix (nucleoside diphosphate linked moiety X)-type motif 3
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Ornithine-oxo-acid Transaminase Activity Pyridoxal Phosphate Binding	Magnesium Ion Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity
	Biological Process	Visual Perception Cellular Amino Acid Biosynthetic Process Protein Hexamerization Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process L-proline Biosynthetic Process	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process
Pathways		Amino acid synthesis and interconversion (transamination) Metabolism of amino acids and derivatives	Synthesis of pyrophosphates in the cytosol Inositol phosphate metabolism
Drugs		Pyridoxal Phosphate L-Ornithine Gabaculine Canaline
Diseases
GWAS			Body mass index ( 20935630) Height ( 19893584)
Protein-Protein Interactions		3 interactors: NUDT3 SLC35F6 UBQLN4	36 interactors: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1
Entrez ID		4942	11165
HPRD ID		02021	14849
Ensembl ID		ENSG00000065154
Uniprot IDs		P04181	O95989
PDB IDs		1GBN 1OAT 2BYJ 2BYL 2CAN 2OAT	2FVV 2Q9P
Enriched GO Terms of Interacting Partners?		Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Inositol Phosphate Metabolic Process Alcohol Catabolic Process	Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Cellular Metabolic Process Protein Targeting Intracellular Transport Protein Localization To Organelle Cellular Localization Cellular Protein Localization Translational Elongation Establishment Of Protein Localization To Organelle Catabolic Process Protein Localization To Membrane Protein Localization Intracellular Protein Transport Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cellular Process Establishment Of Localization In Cell Protein Targeting To ER Cytoplasmic Transport Aromatic Compound Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Protein Transport Protein Localization To Endoplasmic Reticulum DNA Strand Elongation Involved In DNA Replication Establishment Of Protein Localization Branching Involved In Mammary Gland Duct Morphogenesis DNA Strand Elongation Translational Termination Membrane Organization Cellular Macromolecule Catabolic Process Nuclear-transcribed MRNA Catabolic Process Metabolic Process MRNA Catabolic Process Transcription Factor TFIIIB Complex Assembly Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Positive Regulation Of Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Chaperone-mediated Protein Folding Mammary Gland Duct Morphogenesis RNA Catabolic Process Cellular Nitrogen Compound Metabolic Process Response To Interleukin-4 Cellular Protein Complex Disassembly Viral Life Cycle
Tagcloud ?		aacgaaaaa alignments dicistronic dwarf evolve fijivirus fijiviruses frames lugens maize mrdv nilaparvata nlrv nonoverlapping nonphytopathogenic orf2 orfs osdv rbsdv reovirus rough s10 s7 s9 segments sterile strands streaked uuuuuuuaguc
Tagcloud (Difference) ?		aacgaaaaa alignments dicistronic dwarf evolve fijivirus fijiviruses frames lugens maize mrdv nilaparvata nlrv nonoverlapping nonphytopathogenic orf2 orfs osdv rbsdv reovirus rough s10 s7 s9 segments sterile strands streaked uuuuuuuaguc
Tagcloud (Intersection) ?