NRCAM and HSPA12A

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
BioGRID (two hybrid)

		NRCAM	HSPA12A
Gene Name		neuronal cell adhesion molecule	heat shock 70kDa protein 12A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Neuron Projection Axon Initial Segment Synapse	Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Ankyrin Binding Protein Binding Involved In Heterotypic Cell-cell Adhesion	Molecular_function ATP Binding
	Biological Process	Angiogenesis Neuron Migration Axonogenesis Axon Guidance Axonal Fasciculation Synapse Assembly Central Nervous System Development Protein Localization Single Organismal Cell-cell Adhesion Neuronal Action Potential Propagation Regulation Of Axon Extension Retinal Ganglion Cell Axon Guidance Heterotypic Cell-cell Adhesion Clustering Of Voltage-gated Sodium Channels Positive Regulation Of Neuron Differentiation	Biological_process
Pathways		Interaction between L1 and Ankyrins Axon guidance Neurofascin interactions L1CAM interactions NrCAM interactions
Drugs
Diseases
GWAS		Coffee consumption ( 21876539) Femoral neck bone geometry and menarche (age at onset) ( 23593202)	Colorectal cancer ( 23263487)
Protein-Protein Interactions		8 interactors: ANK2 CNTN2 HSPA12A LNX1 MACF1 MAGI3 NFASC PTPRB	1 interactors: NRCAM
Entrez ID		4897	259217
HPRD ID		07207	19074
Ensembl ID		ENSG00000091129	ENSG00000165868
Uniprot IDs		B7Z670 Q14CA1 Q92823	O43301
PDB IDs		1UEN 1UEY
Enriched GO Terms of Interacting Partners?		Protein Localization To Juxtaparanode Region Of Axon Neuronal Ion Channel Clustering Paranodal Junction Assembly Myelination Axon Ensheathment Neuron Maturation Myelin Assembly Membrane Organization Axon Guidance Anatomical Structure Formation Involved In Morphogenesis Establishment Of Protein Localization To Plasma Membrane Establishment Of Protein Localization To Juxtaparanode Region Of Axon Protein Localization To T-tubule Anatomical Structure Morphogenesis Axonogenesis Cellular Protein Localization Protein Localization To M-band Positive Regulation Of Adenosine Receptor Signaling Pathway T-tubule Organization Cell-cell Junction Assembly Axon Development Cell Morphogenesis Involved In Neuron Differentiation Protein Localization To Endoplasmic Reticulum Chemotaxis Movement Of Cell Or Subcellular Component Neuron Projection Morphogenesis Clustering Of Voltage-gated Potassium Channels Generation Of Neurons Cell Maturation Protein Localization To Plasma Membrane Regulation Of Axonogenesis Protein Targeting To Membrane Neurogenesis Cell Morphogenesis Involved In Differentiation Membrane Depolarization During SA Node Cell Action Potential Cell Junction Assembly SA Node Cell Action Potential Neuron Projection Development Cell-cell Junction Organization Cell Projection Morphogenesis Clustering Of Voltage-gated Sodium Channels Regulation Of Axon Diameter Protein Localization Cell Part Morphogenesis Plasma Membrane Organization Posttranslational Protein Targeting To Membrane Regulation Of Cardiac Muscle Cell Membrane Potential Establishment Of Protein Localization To Membrane Cerebral Cortex GABAergic Interneuron Migration Atrial Cardiac Muscle Cell Action Potential	Clustering Of Voltage-gated Sodium Channels Neuronal Action Potential Propagation Neuronal Ion Channel Clustering Retinal Ganglion Cell Axon Guidance Heterotypic Cell-cell Adhesion Axonal Fasciculation Neuron Maturation Neuron Recognition Transmission Of Nerve Impulse Regulation Of Axon Extension Synapse Assembly Cell Recognition Regulation Of Cell Size Cell Maturation Regulation Of Axonogenesis Neuron Migration Synapse Organization
Tagcloud ?		affects clustering disorganization dorsal erbb2 erbb3 ganglion glaucoma gliomedin implicate littermates myelin myelination myocilin nav1 nerve nerves neurofascin nodal nodes null ocular ranvier root schwann sciatic sheath stimulates thickness	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Difference) ?		affects clustering disorganization dorsal erbb2 erbb3 ganglion glaucoma gliomedin implicate littermates myelin myelination myocilin nav1 nerve nerves neurofascin nodal nodes null ocular ranvier root schwann sciatic sheath stimulates thickness	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Intersection) ?