NRCAM and VPS26C

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		NRCAM	VPS26C
Description		neuronal cell adhesion molecule	VPS26 endosomal protein sorting factor C
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Membrane Axon Cell Projection Neuron Projection Axon Initial Segment Synapse Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse	Nucleus Endosome
	Molecular Function	Protein Binding Ankyrin Binding Protein Binding Involved In Heterotypic Cell-cell Adhesion Cell-cell Adhesion Mediator Activity	Protein Binding
	Biological Process	Angiogenesis Neuron Migration Cell Adhesion Axonogenesis Axon Guidance Axonal Fasciculation Synapse Assembly Central Nervous System Development Brain Development Intracellular Protein Localization Regulation Of Neuron Projection Development Neuronal Action Potential Propagation Regulation Of Axon Extension Retinal Ganglion Cell Axon Guidance Heterotypic Cell-cell Adhesion Clustering Of Voltage-gated Sodium Channels Positive Regulation Of Neuron Differentiation Synapse Organization Cell-cell Adhesion Regulation Of Postsynapse Organization	Intracellular Protein Transport Endocytic Recycling
Pathways		Interaction between L1 and Ankyrins NrCAM interactions Neurofascin interactions
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Coffee consumption ( 21876539) Diastolic blood pressure ( 27841878) Femoral neck bone geometry and menarche (age at onset) ( 23593202) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White matter hyperintensities in ischemic stroke ( 26674333) White matter hyperintensity burden ( 25663218)
Interacting Genes		11 interacting genes: ANK2 CNTN2 HSPA12A LCOR LNX1 MACF1 MAGI3 NFASC PTPRB RSPH1 VPS26C	44 interacting genes: AGTPBP1 ARHGAP21 ASH1L CBLB CCDC85A CIPC DCLK1 DDIT4L DECR2 DNAJB2 EPHB6 INCA1 KIF1A KIF21A LRIF1 MAML3 MAPK6 MAPK8IP1 MDM4 MEI4 MEOX2 MRPS35 MYRIP NRCAM NSMF PALS2 PCM1 PEG10 PMS2 PRKD2 PTPN21 RAB39B RAP1GAP RAP1GAP2 SETMAR TAF1C TEPSIN TET2 TRAPPC1 U2AF1 VPS26A VPS35L XPA ZNF655
Entrez ID		4897	10311
HPRD ID		07207	10390
Ensembl ID		ENSG00000091129	ENSG00000157538
Uniprot IDs		A0A1S5UZH4 B7Z670 C9JYY6 Q14CA1 Q92823	A8MTY9 A8MY26 O14972
PDB IDs		1UEN 1UEY	8P0X 8SYN 8SYO 9AU7
Enriched GO Terms of Interacting Partners?		Node Of Ranvier Axon Initial Segment
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