NPY5R and PYY

Number of citations of the paper that reports this interaction (PMID 12665544)
12

Data Source:
HPRD (in vivo)

		NPY5R	PYY
Gene Name		neuropeptide Y receptor Y5	peptide YY
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Extracellular Region Extracellular Space
	Molecular Function	Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity Neuropeptide Y Receptor Activity	G-protein Coupled Receptor Binding Hormone Activity Neuropeptide Hormone Activity Protein Binding
	Biological Process	Positive Regulation Of Acute Inflammatory Response Outflow Tract Morphogenesis Cardiac Left Ventricle Morphogenesis G-protein Coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Synaptic Transmission Negative Regulation Of Glutamate Secretion Negative Regulation Of Synaptic Transmission, GABAergic Eating Behavior Negative Regulation Of Apoptotic Process Positive Regulation Of Smooth Muscle Cell Proliferation Generation Of Ovulation Cycle Rhythm	Movement Of Cell Or Subcellular Component Cytoskeleton Organization G-protein Coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Cell-cell Signaling Digestion Feeding Behavior Cell Proliferation Regulation Of Appetite Eating Behavior
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS			Response to taxane treatment (placlitaxel) ( 23006423)
Protein-Protein Interactions		4 interactors: NPY NUPR1 PYY RNF181	5 interactors: MEP1B NPY1R NPY2R NPY4R NPY5R
Entrez ID		4889	5697
HPRD ID		03591	02869
Ensembl ID		ENSG00000164129	ENSG00000131096
Uniprot IDs		Q15761	P10082
PDB IDs		2HE6	2DEZ 2DF0 2L60
Enriched GO Terms of Interacting Partners?		Regulation Of Appetite Neuropeptide Signaling Pathway Feeding Behavior Digestion Positive Regulation Of Appetite Adult Feeding Behavior Response To Nutrient Levels Regulation Of Female Gonad Development Response To Extracellular Stimulus Regulation Of Response To Food Behavior	Neuropeptide Signaling Pathway Outflow Tract Morphogenesis Feeding Behavior Synaptic Transmission Behavior Cardiac Left Ventricle Morphogenesis Heart Morphogenesis Cell-cell Signaling G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Synaptic Transmission Cardiac Ventricle Morphogenesis Heart Development Cardiac Ventricle Development Generation Of Ovulation Cycle Rhythm Digestion Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Regulation Of Anion Transport Cardiac Chamber Development G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cardiovascular System Development Negative Regulation Of Secretion Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Organ Morphogenesis Locomotory Behavior Positive Regulation Of Dopamine Secretion Negative Regulation Of Feeding Behavior Negative Regulation Of Glutamate Secretion Cell Surface Receptor Signaling Pathway Negative Regulation Of Synaptic Transmission, GABAergic Negative Regulation Of Excitatory Postsynaptic Membrane Potential Blood Circulation Regulation Of Synaptic Transmission Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Catecholamine Secretion Regulation Of Glutamate Secretion Negative Regulation Of Transport Negative Regulation Of Membrane Potential Regulation Of Feeding Behavior Negative Regulation Of Neurological System Process Negative Regulation Of Synaptic Transmission, Glutamatergic Nitric Oxide Mediated Signal Transduction Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of Circadian Rhythm Regulation Of Dopamine Secretion Response To Stimulus Regulation Of Sensory Perception Of Pain Positive Regulation Of Acute Inflammatory Response Positive Regulation Of Smooth Muscle Contraction Negative Regulation Of CAMP Biosynthetic Process
Tagcloud ?		advance atp5j differs doi erythroleukemia exerts gtf2a2 lep lim lipoma lpp m133k march mpn neoplasm npy1r onc online persistently platelets preferred promoters publication recruit stat5 synergistically thrombopoietin transducer vegfc	antiperoxidase antiserum bile bombesin charcoal coated dextran granules hormonal ileum immunohistochemically intraduodenal iv oleate pap peroxidase pg pmol pole rabbits radioimmunoassay raised ria rose secretory terminate triglyceride zealand
Tagcloud (Difference) ?		advance atp5j differs doi erythroleukemia exerts gtf2a2 lep lim lipoma lpp m133k march mpn neoplasm npy1r onc online persistently platelets preferred promoters publication recruit stat5 synergistically thrombopoietin transducer vegfc	antiperoxidase antiserum bile bombesin charcoal coated dextran granules hormonal ileum immunohistochemically intraduodenal iv oleate pap peroxidase pg pmol pole rabbits radioimmunoassay raised ria rose secretory terminate triglyceride zealand
Tagcloud (Intersection) ?