NPY5R and RNF181

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NPY5R	RNF181
Gene Name		neuropeptide Y receptor Y5	ring finger protein 181
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity Neuropeptide Y Receptor Activity	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Positive Regulation Of Acute Inflammatory Response Outflow Tract Morphogenesis Cardiac Left Ventricle Morphogenesis G-protein Coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Synaptic Transmission Negative Regulation Of Glutamate Secretion Negative Regulation Of Synaptic Transmission, GABAergic Eating Behavior Negative Regulation Of Apoptotic Process Positive Regulation Of Smooth Muscle Cell Proliferation Generation Of Ovulation Cycle Rhythm	Protein Autoubiquitination
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS			Prostate cancer ( 21743467)
Protein-Protein Interactions		4 interactors: NPY NUPR1 PYY RNF181	19 interactors: BIRC2 BTG1 CLK4 MRPS6 NPY5R PEG10 RBCK1 TRIM24 TRIM8 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2U VPS11 ZMYND10
Entrez ID		4889	51255
HPRD ID		03591	14236
Ensembl ID		ENSG00000164129
Uniprot IDs		Q15761	Q9P0P0
PDB IDs		2HE6
Enriched GO Terms of Interacting Partners?		Regulation Of Appetite Neuropeptide Signaling Pathway Feeding Behavior Digestion Positive Regulation Of Appetite Adult Feeding Behavior Response To Nutrient Levels Regulation Of Female Gonad Development Response To Extracellular Stimulus Regulation Of Response To Food Behavior	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Toll-like Receptor 4 Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cellular Protein Modification Process Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Positive Regulation Of Innate Immune Response Protein K11-linked Ubiquitination Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Immune Response-regulating Signaling Pathway Regulation Of Innate Immune Response Cellular Response To Oxygen Levels Response To Hypoxia Catabolic Process Positive Regulation Of Protein Ubiquitination Protein Metabolic Process Positive Regulation Of Immune Response Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteolysis Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Innate Immune Response Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Ligase Activity Negative Regulation Of Necroptotic Process
Tagcloud ?		advance atp5j differs doi erythroleukemia exerts gtf2a2 lep lim lipoma lpp m133k march mpn neoplasm npy1r onc online persistently platelets preferred promoters publication recruit stat5 synergistically thrombopoietin transducer vegfc
Tagcloud (Difference) ?		advance atp5j differs doi erythroleukemia exerts gtf2a2 lep lim lipoma lpp m133k march mpn neoplasm npy1r onc online persistently platelets preferred promoters publication recruit stat5 synergistically thrombopoietin transducer vegfc
Tagcloud (Intersection) ?