PYY

Name	peptide YY
Structure
Interactors	6 interactors: MEP1B NPY1R NPY2R NPY4R NPY5R SGTA
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	G Protein-coupled Receptor Binding Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuropeptide Y Receptor Binding
	Biological Process	Neuropeptide Signaling Pathway Feeding Behavior Intestinal Epithelial Cell Differentiation
Pathways	Peptide ligand-binding receptors G alpha (i) signalling events
GWAS	Blood protein levels ( 30072576 ) Diverticular disease ( 30177863 ) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223 ) HDL levels x fish oil supplementation interaction (2df) ( 33760818 ) Pulse pressure ( 28135244 ) Response to taxane treatment (paclitaxel) ( 23006423 ) Triglyceride levels ( 32203549 )
Entrez ID	5697
HPRD ID	02869
Ensembl ID	ENSG00000131096
Uniprot IDs	P10082
PDB IDs	2DEZ 2DF0 2L60 2NA5 7RT9 7YON
GO Terms Enriched among Interactors ?	Neuropeptide Y Receptor Activity Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity Neuropeptide Signaling Pathway Neuropeptide Binding Outflow Tract Morphogenesis G Protein-coupled Receptor Activity Synaptic Signaling Via Neuropeptide Cardiac Left Ventricle Morphogenesis Signaling Cell Communication Cardiac Ventricle Morphogenesis G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Synaptic Transmission Neuron Projection Regulation Of Amine Transport Feeding Behavior Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Generation Of Ovulation Cycle Rhythm Meprin A Complex TRC Complex Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Synaptic Transmission, GABAergic BAT3 Complex Binding Negative Regulation Of Secretion Negative Regulation Of Glutamate Secretion Locomotory Behavior Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Dopamine Secretion Negative Regulation Of Feeding Behavior Negative Regulation Of ERAD Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Presynapse Negative Regulation Of Synaptic Transmission, Glutamatergic Negative Regulation Of Excitatory Postsynaptic Potential Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Membrane Positive Regulation Of Catecholamine Secretion Negative Regulation Of Acute Inflammatory Response Negative Regulation Of Amino Acid Transport Regulation Of Acute Inflammatory Response To Antigenic Stimulus Tail-anchored Membrane Protein Insertion Into ER Membrane Plasma Membrane Synaptic Signaling Neuropeptide Receptor Activity Positive Regulation Of Circadian Rhythm Negative Regulation Of Nervous System Process Nitric Oxide Mediated Signal Transduction