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PNP and RBM48
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PNP
RBM48
Gene Name
purine nucleoside phosphorylase
RNA binding motif protein 48
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Cytoplasm
Cytosol
Cytoskeleton
Extracellular Vesicular Exosome
Nucleoplasm
Molecular Function
Nucleoside Binding
Purine Nucleobase Binding
Purine-nucleoside Phosphorylase Activity
Drug Binding
Phosphate Ion Binding
RNA Binding
Biological Process
Nucleobase-containing Compound Metabolic Process
Purine Nucleobase Metabolic Process
Inosine Catabolic Process
Purine Nucleotide Catabolic Process
Nicotinamide Riboside Catabolic Process
Immune Response
NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway
Urate Biosynthetic Process
Positive Regulation Of T Cell Proliferation
Response To Drug
Purine-containing Compound Salvage
Small Molecule Metabolic Process
Positive Regulation Of Alpha-beta T Cell Differentiation
Nucleobase-containing Small Molecule Metabolic Process
Interleukin-2 Secretion
Pathways
Purine catabolism
Purine metabolism
Metabolism of nucleotides
Purine salvage
Drugs
Cladribine
Didanosine
8-azaguanine
2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine
Immucillin-G
Guanine
2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One
Peldesine
9-Deazainosine
Guanosine
Ribose-1-Phosphate
4\'-Deaza-1\'-Aza-2\'-Deoxy-1\'-(9-Methylene)-Immucillin-H, (3r,4r)-N-[9-Deazahypoxanthin-9-Yl)Methyl]-4-Hydroxymethyl-Pyrrolidin-3-Ol
3-Deoxyguanosine
MT-Immucillin-H
Hypoxanthine
9-(5,5-Difluoro-5-Phosphonopentyl)Guanine
9-DEAZAINOSINE-2\',3\'-O-ETHYLIDENEPHOSPHONATE
GUANOSINE-2\',3\'-O-ETHYLIDENEPHOSPHONATE
GUANOSINE-2\',3\'-O-METHYLIDENEPHOSPHONATE
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
APLP1
CCDC90B
LRIF1
NCALD
RBM48
TFAM
TFB2M
TP53
UCHL5
ZHX1
50 interactors:
ANXA7
APLP1
BID
BTBD2
C11orf49
CCDC106
CDK5RAP2
CDKN1A
CDKN2C
COX17
ERH
FAM118B
FXYD6
GADD45G
GLYAT
GSE1
GSTO1
HSPB1
HSPB3
ID2
KPNA2
MAFG
MAP7D1
MLLT3
MNAT1
MPHOSPH6
NUDT21
OSGEP
PAFAH1B3
PCDHA4
PNP
PPP1R8
PRG2
PSMD11
RAB27A
RFC5
RPA2
SAT1
SERPINB9
SH3GL3
SMN1
SULT1E1
TAF9
TK1
TNFSF10
TRDMT1
TRIB3
VIM
WDR33
ZNF24
Entrez ID
4860
84060
HPRD ID
01247
13173
Ensembl ID
ENSG00000127993
Uniprot IDs
P00491
B4DGJ6
B7Z2K5
Q5RL73
PDB IDs
1M73
1PF7
1PWY
1RCT
1RFG
1RR6
1RSZ
1RT9
1ULA
1ULB
1V2H
1V3Q
1V41
1V45
1YRY
2A0W
2A0X
2A0Y
2OC4
2OC9
2ON6
2Q7O
3BGS
3D1V
3GB9
3GGS
3INY
3K8O
3K8Q
3PHB
4EAR
4EB8
4ECE
4GKA
Enriched GO Terms of Interacting Partners
?
Transcription Initiation From Mitochondrial Promoter
Transcription From Mitochondrial Promoter
RNA Metabolic Process
Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Mitochondrion Organization
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Macromitophagy
Oligodendrocyte Apoptotic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Helicase Activity
Cellular Response To Norepinephrine Stimulus
Biosynthetic Process
Regulation Of Cellular Response To Growth Factor Stimulus
Cellular Response To Transforming Growth Factor Beta Stimulus
Brain Development
Response To Transforming Growth Factor Beta
Regulation Of Metabolic Process
Head Development
Positive Regulation Of Cell Aging
Positive Regulation Of Thymocyte Apoptotic Process
Response To Norepinephrine
Mitochondrial DNA Repair
DNA-templated Transcription, Initiation
Regulation Of Mitochondrion Degradation
T Cell Proliferation Involved In Immune Response
B Cell Lineage Commitment
Glial Cell Apoptotic Process
Oxidative Stress-induced Premature Senescence
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Metabolic Process
Central Nervous System Development
ER Overload Response
Nitrogen Compound Metabolic Process
Mitotic Cell Cycle Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Cell Cycle Phase Transition
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Developmental Process
Response To Stimulus
Central Nervous System Development
MRNA Polyadenylation
Nucleoside Metabolic Process
Negative Regulation Of Transferase Activity
RNA Polyadenylation
Regulation Of Cell Cycle
Negative Regulation Of Protein Kinase Activity
Regulation Of Mitotic Cell Cycle Phase Transition
Mitotic Cell Cycle
Apoptotic Process
Transcription-coupled Nucleotide-excision Repair
Negative Regulation Of Kinase Activity
Regulation Of Cell Cycle Phase Transition
Response To Stress
Negative Regulation Of Catalytic Activity
Programmed Cell Death
Negative Regulation Of Cellular Protein Metabolic Process
Cell Death
Death
MRNA Processing
Multicellular Organismal Development
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Cellular Response To DNA Damage Stimulus
Response To Xenobiotic Stimulus
Regulation Of Cellular Protein Metabolic Process
Nervous System Development
Negative Regulation Of Protein Metabolic Process
Anatomical Structure Development
Mitotic Cell Cycle Process
Regulation Of Cell Cycle Process
Cellular Metabolic Process
Negative Regulation Of Protein Phosphorylation
Mitotic G1 DNA Damage Checkpoint
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Cellular Response To Stress
Positive Regulation Of Cell Cycle Arrest
Tagcloud
?
adenylylimidodiphosphate
altering
amp
analog
anion
anions
atp
channel
cl
closed
conductance
electrogenic
flowed
flux
hidden
hill
lumen
markov
mv
nonhydrolyzable
pass
rectification
ruled
sarcoplasmic
sr
substates
unlikely
voltage
voltages
Tagcloud (Difference)
?
adenylylimidodiphosphate
altering
amp
analog
anion
anions
atp
channel
cl
closed
conductance
electrogenic
flowed
flux
hidden
hill
lumen
markov
mv
nonhydrolyzable
pass
rectification
ruled
sarcoplasmic
sr
substates
unlikely
voltage
voltages
Tagcloud (Intersection)
?