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NDUFS2 and HMOX2
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
NDUFS2
HMOX2
Gene Name
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
heme oxygenase (decycling) 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Respiratory Chain Complex I
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Molecular Function
NADH Dehydrogenase Activity
Protein Binding
NADH Dehydrogenase (ubiquinone) Activity
Electron Carrier Activity
Metal Ion Binding
Quinone Binding
NAD Binding
4 Iron, 4 Sulfur Cluster Binding
Heme Oxygenase (decyclizing) Activity
Protein Binding
Metal Ion Binding
Biological Process
Mitochondrial Electron Transport, NADH To Ubiquinone
Response To Oxidative Stress
Respiratory Electron Transport Chain
Cellular Metabolic Process
Small Molecule Metabolic Process
Response To Hypoxia
Porphyrin-containing Compound Metabolic Process
Heme Oxidation
Cellular Iron Ion Homeostasis
Heme Catabolic Process
Small Molecule Metabolic Process
Transmembrane Transport
Pathways
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Respiratory electron transport
The citric acid (TCA) cycle and respiratory electron transport
Iron uptake and transport
Metabolism of porphyrins
Heme degradation
Drugs
NADH
NADH
Diseases
GWAS
Protein-Protein Interactions
5 interactors:
APP
CENPU
EGR2
HMOX2
TNFRSF14
32 interactors:
A2M
APP
ATP5B
BLOC1S2
CEBPZ
COPS6
CSNK2A1
EEF1G
EIF3C
GIT1
GPRASP1
HAP1
IMMT
INPP5K
ITFG1
JADE1
KCNMA1
KIAA1377
LRIF1
MED31
NDUFS2
NKRF
NR3C1
PLXNB2
RBBP4
SETDB1
SHC1
SKA2
SNX5
SNX7
ZFP28
ZNF746
Entrez ID
4720
3163
HPRD ID
04285
00783
Ensembl ID
ENSG00000158864
ENSG00000103415
Uniprot IDs
B7Z792
O75306
I3L430
P30519
PDB IDs
2Q32
2QPP
2RGZ
Enriched GO Terms of Interacting Partners
?
Rhombomere 5 Formation
Rhombomere 3 Formation
Transition Metal Ion Homeostasis
Rhombomere 3 Morphogenesis
Synaptic Growth At Neuromuscular Junction
Brain Segmentation
Collateral Sprouting In Absence Of Injury
Heme Oxidation
Regulation Of Peptidyl-tyrosine Phosphorylation
Rhombomere 3 Development
Rhombomere 5 Development
Positive Regulation Of Cytokine Secretion Involved In Immune Response
Collateral Sprouting
Axon Midline Choice Point Recognition
Rhombomere Morphogenesis
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Learning Or Memory
Axon Choice Point Recognition
Locomotion
Cognition
Negative Regulation Of Alpha-beta T Cell Proliferation
Heme Catabolic Process
Neuron Remodeling
Rhombomere Development
Facial Nerve Structural Organization
Regulation Of Cytokine Secretion Involved In Immune Response
Axon Guidance
Facial Nerve Morphogenesis
Regulation Of Cellular Amino Acid Metabolic Process
Cellular Metal Ion Homeostasis
Response To Oxidative Stress
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Positive Regulation Of T Cell Migration
Single-organism Behavior
Metal Ion Homeostasis
Cellular Copper Ion Homeostasis
Response To External Stimulus
Rhythmic Behavior
Regulation Of T Cell Migration
Parasympathetic Nervous System Development
Regulation Of Cellular Ketone Metabolic Process
Anatomical Structure Arrangement
Copper Ion Homeostasis
Suckling Behavior
Axonogenesis
Cellular Chemical Homeostasis
Negative Regulation Of Alpha-beta T Cell Activation
Viral Process
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Axon Cargo Transport
Cellular Macromolecule Biosynthetic Process
Organelle Organization
Macromolecule Biosynthetic Process
RNA Metabolic Process
Biosynthetic Process
Regulation Of Transcription, DNA-templated
Cellular Process
Regulation Of Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of ERBB Signaling Pathway
Regulation Of Mitotic Cell Cycle Phase Transition
Nucleobase-containing Compound Metabolic Process
Regulation Of Cell Cycle Phase Transition
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cell Cycle Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Receptor Activity
Cell Projection Organization
Cellular Nitrogen Compound Metabolic Process
Anterograde Axon Cargo Transport
Microtubule-based Transport
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Regulation Of Body Fluid Levels
Cytoskeleton-dependent Intracellular Transport
Regulation Of Cell Cycle
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Neurotrophin Production
Positive Regulation Of Nonmotile Primary Cilium Assembly
Glucocorticoid Mediated Signaling Pathway
Positive Regulation Of Renal Water Transport
Regulation Of Cellular Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Signal Transduction
Cellular Response To CAMP
Cellular Homeostasis
Regulation Of Mitotic Cell Cycle
Platelet Activation
Tagcloud
?
accounting
agf3l2
assembly
c20orf7
c8orf38
chase
confirming
docks
holoenzyme
immunoprecipitated
knock
knocked
labeling
module
mtdna
nadh
nd1
ndufa9
ndufaf3
ndufaf4
nucleating
oxidoreductase
proteolysis
pulse
redundant
stabilizes
ubiquinone
Tagcloud (Difference)
?
accounting
agf3l2
assembly
c20orf7
c8orf38
chase
confirming
docks
holoenzyme
immunoprecipitated
knock
knocked
labeling
module
mtdna
nadh
nd1
ndufa9
ndufaf3
ndufaf4
nucleating
oxidoreductase
proteolysis
pulse
redundant
stabilizes
ubiquinone
Tagcloud (Intersection)
?