MEIS2 and TLX1

Number of citations of the paper that reports this interaction (PubMedID 16357834)
0

Data Source:
BioGRID (pull down)

		MEIS2	TLX1
Description		Meis homeobox 2	T cell leukemia homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Perinuclear Region Of Cytoplasm	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of DNA-templated Transcription Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Development
Pathways
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Postprandial triglyceride response ( 32603185) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimer’s disease ( 30584014)	Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889)
Interacting Genes		50 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 CARTPT CCDC196 CTAG1A CTAG1B DGCR6 DRD1 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SPMIP6 SQSTM1 TBX2 TIMM10B TLX1 TRIM25 TRIM42 VGLL1 ZNHIT3	11 interacting genes: CTF1 EIF4E MEIS1 MEIS2 NFIC PKNOX1 PPP1CB PPP1CC PPP2CA PPP2CB TLE1
Entrez ID		4212	3195
HPRD ID		03443	01728
Ensembl ID		ENSG00000134138	ENSG00000107807
Uniprot IDs		B3KPD8 B7Z6F6 O14770	P31314
PDB IDs		3K2A 4XRM 5BNG 5EG0
Enriched GO Terms of Interacting Partners?		Intermediate Filament Positive Regulation Of Long-term Synaptic Potentiation	Protein Serine/threonine Phosphatase Activity Protein Dephosphorylation Phosphoprotein Phosphatase Activity Dephosphorylation Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process PTW/PP1 Phosphatase Complex Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Protein Phosphatase Type 2A Complex FAR/SIN/STRIPAK Complex Eye Development Response To Lead Ion Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Chromosome, Centromeric Region Sensory Organ Development Animal Organ Morphogenesis Chromatin Nucleus Tau Protein Binding Transcription Regulator Complex Developmental Process Eukaryotic Initiation Factor 4G Binding Negative Regulation Of Cell Differentiation Embryonic Pattern Specification Glycogen Metabolic Process Myosin-light-chain-phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Transcription By RNA Polymerase II Regulation Of Microtubule Polymerization Circadian Regulation Of Gene Expression Negative Regulation Of Neuron Differentiation Response To Light Stimulus Energy Reserve Metabolic Process Polysaccharide Metabolic Process Phosphatase Activity Leukemia Inhibitory Factor Receptor Binding RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Neuron Differentiation Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Cell Population Proliferation Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Regulation Of Cell Differentiation Positive Regulation Of Cardiac Muscle Myoblast Proliferation Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Developmental Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?