HPCAL4 and TRPM5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HPCAL4	TRPM5
Description		hippocalcin like 4	transient receptor potential cation channel subfamily M member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Plasma Membrane Membrane Dendrite Monoatomic Ion Channel Complex Neuronal Cell Body
	Molecular Function	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Protein Domain Specific Binding Metal Ion Binding	Monoatomic Ion Channel Activity Calcium-activated Cation Channel Activity Potassium Channel Activity Sodium Channel Activity Calcium Ion Binding Protein Binding Identical Protein Binding Metal Ion Binding Metal Ion Transmembrane Transporter Activity
	Biological Process	Central Nervous System Development Response To Heat Regulation Of Signal Transduction	Monoatomic Ion Transport Metal Ion Transport Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Transmembrane Transport Calcium Ion Transmembrane Transport Potassium Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport
Pathways			TRP channels Sensory perception of sweet, bitter, and umami (glutamate) taste
Drugs
Diseases
GWAS		Bone mineral density (Ward's triangle area) ( 27397699)	Malaria ( 31844061) Metabolite levels ( 23823483)
Interacting Genes		16 interacting genes: ANKRD33 AQP4 CDSN CEACAM6 DTX2 F3 FAM131C LITAF MSRA SCMH1 SPRED1 TEX13B TRPM5 TSC22D3 TTC12 UBE3A	1 interacting genes: HPCAL4
Entrez ID		51440	29850
HPRD ID		17113	16064
Ensembl ID		ENSG00000116983	ENSG00000070985
Uniprot IDs		B4DGW9 Q9UM19	Q9NZQ8
PDB IDs
Enriched GO Terms of Interacting Partners?			Central Nervous System Development Response To Temperature Stimulus Calcium Channel Regulator Activity Response To Heat
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