NAP1L2 and SH3BP5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NAP1L2	SH3BP5
Description		nucleosome assembly protein 1 like 2	SH3 domain binding protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Cytoplasm Mitochondrion Membrane Nuclear Body Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Chromatin Binding Protein Binding Histone Acetyltransferase Regulator Activity Histone Binding	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding SH3 Domain Binding
	Biological Process	Nucleosome Assembly Neuron Differentiation Positive Regulation Of Neuron Differentiation Regulation Of Stem Cell Division	Signal Transduction Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Alcohol and nicotine co-dependence ( 22488850) Alcohol dependence ( 21956439) Heschl's gyrus morphology ( 25130324) Prudent dietary pattern ( 28644415)
Interacting Genes		14 interacting genes: CCDC146 CCDC185 DMAP1 FAM81A KLHL2 MED30 NAP1L1 NAP1L5 OLIG2 PPP1R13B PPP3R1 SCNM1 SH3BP5 SP110	16 interacting genes: APP BTK CDC5L DISC1 DST EXOC1 IFT20 MAPK10 MAPK12 MAPK8 MAPK9 NAP1L2 SOS1 SPTBN1 SYNE1 TTC3
Entrez ID		4674	9467
HPRD ID		02066	12030
Ensembl ID		ENSG00000186462	ENSG00000131370
Uniprot IDs		Q9ULW6	O60239
PDB IDs			4H3B 6DJL 6IXE 6IXF 6IXG 6IXV
Enriched GO Terms of Interacting Partners?			Fc-epsilon Receptor Signaling Pathway JUN Kinase Activity MAP Kinase Activity Fc Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Intracellular Signaling Cassette Intracellular Signal Transduction Cytoplasm Cell Surface Receptor Signaling Pathway Peptidase Activator Activity Immune Response-regulating Signaling Pathway JNK Cascade Cellular Senescence MAPK Cascade Protein Kinase Activity Positive Regulation Of Cell Differentiation Regulation Of Immune Response Cellular Response To Reactive Oxygen Species Regulation Of Circadian Rhythm Response To Light Stimulus Kinase Activity Protein Serine/threonine Kinase Binding Regulation Of Cell Differentiation Signal Transduction Protein Phosphorylation Protein Serine Kinase Activity Positive Regulation Of Cellular Component Organization Phosphorylation Axon Cytosol Response To Reactive Oxygen Species Positive Regulation Of NLRP3 Inflammasome Complex Assembly Protein Serine/threonine Kinase Activity Transport Along Microtubule Regulation Of Protein-containing Complex Assembly Response To Radiation Positive Regulation Of Proteolysis Amyloid-beta Complex Growth Cone Lamellipodium Cytoskeleton-dependent Intracellular Transport Regulation Of Response To Calcium Ion Response To Stress Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Developmental Process Regulation Of B Cell Cytokine Production Monocyte Proliferation Positive Regulation Of Interleukin-17A Production Cellular Response To Oxidative Stress Positive Regulation Of Protein-containing Complex Assembly
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