NAP1L2 and NAP1L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NAP1L2	NAP1L1
Description		nucleosome assembly protein 1 like 2	nucleosome assembly protein 1 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus Cytoplasm Membrane Melanosome
	Molecular Function	Chromatin Binding Protein Binding Histone Acetyltransferase Regulator Activity Histone Binding	Chromatin Binding RNA Binding Protein Binding Histone Binding Histone Chaperone Activity
	Biological Process	Nucleosome Assembly Neuron Differentiation Positive Regulation Of Neuron Differentiation Regulation Of Stem Cell Division	DNA Replication Nucleosome Assembly Nervous System Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of Neural Precursor Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Obesity-related traits ( 23251661) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)
Interacting Genes		14 interacting genes: CCDC146 CCDC185 DMAP1 FAM81A KLHL2 MED30 NAP1L1 NAP1L5 OLIG2 PPP1R13B PPP3R1 SCNM1 SH3BP5 SP110	34 interacting genes: ANKRD23 C1QTNF9 CHORDC1 CREBBP CSNK2A1 CSNK2B DLST DYRK1A EP300 ERCC6 FSD1 GAS2L2 H1-1 H4C1 HBA1 HMGB2 HSPB1 ISG15 LINC01554 MED10 MTNR1A NAP1L2 NR2F6 OGT POT1 RPL23 RPL23A RPS15 SNCA SP1 SUMO2 TERF1 TP53 TPX2
Entrez ID		4674	4673
HPRD ID		02066	01248
Ensembl ID		ENSG00000186462	ENSG00000187109
Uniprot IDs		Q9ULW6	B7Z2V4 F5H4R6 F8W543 P55209 Q9H2B0
PDB IDs			7BP5 7UN3 7UN6
Enriched GO Terms of Interacting Partners?			Rhythmic Process Regulation Of Protein Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Nucleoplasm Negative Regulation Of DNA Metabolic Process Nucleus Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cellular Response To Stress Regulation Of Cellular Response To Heat Transcription Coactivator Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Histone H3K27 Acetyltransferase Activity Tau Protein Binding Negative Regulation Of Cellular Component Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Histone H3K18 Acetyltransferase Activity Double-strand Break Repair N-terminal Peptidyl-lysine Acetylation Chromatin Remodeling Cellular Component Assembly Peptide Lactyltransferase (CoA-dependent) Activity Chromatin Organization Regulation Of Cellular Component Organization Protein Localization To Organelle Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Double-strand Break Repair Via Nonhomologous End Joining Symbiont-mediated Disruption Of Host Cell PML Body Circadian Rhythm Negative Regulation Of Telomere Maintenance Via Telomerase Cellular Response To Actinomycin D Negative Regulation Of Proteolysis Positive Regulation Of Metabolic Process Histone Acetyltransferase Complex Negative Regulation Of Catabolic Process Regulation Of Proteolysis Regulation Of Microtubule-based Process Response To Actinomycin D Regulation Of Primary Metabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Amide Metabolic Process Regulation Of Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Chromatin DNA Binding Regulation Of Protein-containing Complex Assembly Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of G1 To G0 Transition
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