NAP1L2 and SP110

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		NAP1L2	SP110
Gene Name		nucleosome assembly protein 1-like 2	SP110 nuclear body protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleolus
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	DNA Binding Chromatin Binding Signal Transducer Activity Zinc Ion Binding
	Biological Process	Nucleosome Assembly Positive Regulation Of Neuron Differentiation Positive Regulation Of Histone H3-K14 Acetylation Regulation Of Stem Cell Division Positive Regulation Of Histone H3-K9 Acetylation	Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Signal Transduction Viral Process
Pathways
Drugs
Diseases
GWAS			Chronic lymphocytic leukemia ( 18758461) Obesity-related traits ( 23251661)
Protein-Protein Interactions		2 interactors: PPP3R1 SP110	11 interactors: ANXA7 CDKN1A NAP1L2 NDUFV2 OSGEP RUNX3 SMN1 TK1 TSC22D1 TTR ZSCAN9
Entrez ID		4674	3431
HPRD ID		02066	06832
Ensembl ID		ENSG00000186462	ENSG00000135899
Uniprot IDs		Q9ULW6	G5E9C0 Q9HB58
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of NFAT Protein Import Into Nucleus Calcineurin-NFAT Signaling Cascade Inositol Phosphate-mediated Signaling Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Transcription Factor Import Into Nucleus	Nucleoside Metabolic Process Fetal Process Involved In Parturition Positive Regulation Of Histone H3-K14 Acetylation Threonylcarbamoyladenosine Biosynthetic Process Skeletal Muscle Cell Proliferation Cellular Metabolic Process Regulation Of Histone H3-K14 Acetylation Nucleobase-containing Compound Metabolic Process Digestive Tract Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Maturation Digestive System Development Positive Regulation Of Programmed Cell Death Threonylcarbamoyladenosine Metabolic Process Thyroid Hormone Transport Intestinal Epithelial Cell Maturation Anatomical Structure Development Response To Glucocorticoid Positive Regulation Of Cell Death Response To Corticosteroid Cellular Nitrogen Compound Metabolic Process Response To Cortisol Thymidine Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Response To Toxic Substance Regulation Of Stem Cell Division Positive Regulation Of Histone H3-K9 Acetylation Cellular Response To UV-B Deoxyribonucleoside Monophosphate Biosynthetic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Developmental Process Nitrogen Compound Metabolic Process
Tagcloud ?		1c acetylated acetylation assembly associates cdkn1c chromatin correlates defects deficiencies differentiating downregulation establishment h3k9 h4 histones idea interacts maintenance marked mediate modification neural neurogenesis neuronal normally nucleosome permissive tube	cavitary cc classification ct dimensionality employed except explore fresh gc genotype heterozygous homozygous instead mtb multifactor mybbp1a mycobacterium pathological progress promising ptb rela rs3809849 rs9061 rs9905742 tree tuberculosis whole
Tagcloud (Difference) ?		1c acetylated acetylation assembly associates cdkn1c chromatin correlates defects deficiencies differentiating downregulation establishment h3k9 h4 histones idea interacts maintenance marked mediate modification neural neurogenesis neuronal normally nucleosome permissive tube	cavitary cc classification ct dimensionality employed except explore fresh gc genotype heterozygous homozygous instead mtb multifactor mybbp1a mycobacterium pathological progress promising ptb rela rs3809849 rs9061 rs9905742 tree tuberculosis whole
Tagcloud (Intersection) ?