NACA and BTF3

Number of citations of the paper that reports this interaction (PMID 10982809)
15

Data Source:
BioGRID (pull down)

		NACA	BTF3
Gene Name		nascent polypeptide-associated complex alpha subunit	basic transcription factor 3
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Nascent Polypeptide-associated Complex Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding TBP-class Protein Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Cardiac Ventricle Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Negative Regulation Of Striated Muscle Cell Apoptotic Process Protein Transport Viral Process Skeletal Muscle Tissue Regeneration Positive Regulation Of Skeletal Muscle Tissue Growth Regulation Of Skeletal Muscle Fiber Development Heart Trabecula Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis	In Utero Embryonic Development Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Protein Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: APLP1 BTF3 CCDC90B FADD FOS FUNDC2 IGSF21 JUN LRIF1 MDM2 NUPR1 SMYD1 SPP1 TBP TXLNA UCHL5 ZHX1	9 interactors: APP CSNK2B ESR1 MED21 NACA POLR2B TXLNA TXLNB ZDHHC17
Entrez ID		4666	689
HPRD ID		03137	03966
Ensembl ID		ENSG00000196531	ENSG00000145741
Uniprot IDs		B2R4P8 Q13765	P20290
PDB IDs		3LKX 3MCB 3MCE	3LKX 3MCB
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Skeletal Muscle Cell Differentiation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Myeloid Cell Differentiation Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Regulation Of Myeloid Leukocyte Differentiation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Nucleobase-containing Compound Metabolic Process Skeletal Muscle Tissue Development Cellular Macromolecule Biosynthetic Process Activation Of Innate Immune Response Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Defense Response Macromolecule Biosynthetic Process Skeletal Muscle Organ Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Response To Organic Cyclic Compound Response To Extracellular Stimulus Immune Response-regulating Signaling Pathway Immune System Process Regulation Of Myeloid Cell Differentiation Organ Development Response To Toxic Substance Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Innate Immune Response Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Response To Reactive Oxygen Species Apoptotic Process Programmed Cell Death Cellular Response To Extracellular Stimulus Response To Mechanical Stimulus	Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Developmental Growth Cell Development Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Growth Positive Regulation Of Transcription, DNA-templated Synaptic Growth At Neuromuscular Junction Hormone-mediated Signaling Pathway Collateral Sprouting In Absence Of Injury Positive Regulation Of Skeletal Muscle Tissue Growth Prostate Epithelial Cord Elongation Developmental Growth Involved In Morphogenesis Regulation Of Cell Differentiation Stem Cell Maintenance Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Cell Differentiation Anatomical Structure Development Regulation Of Organ Morphogenesis Collateral Sprouting Axon Midline Choice Point Recognition Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway RNA Metabolic Process Intracellular Receptor Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Regulation Of Transcription From RNA Polymerase II Promoter Axon Choice Point Recognition Cell Differentiation Gene Expression DNA-templated Transcription, Initiation Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Developmental Process Adiponectin-activated Signaling Pathway Regulation Of Branching Involved In Prostate Gland Morphogenesis Mammary Gland Branching Involved In Pregnancy Cellular Macromolecule Biosynthetic Process Steroid Metabolic Process Stem Cell Development Neuron Remodeling Regulation Of Binding Macromolecule Biosynthetic Process
Tagcloud ?		ap apd20 apd50 apd90 atrial caf cal calibrate calibrated determines deviating electrophysiology explaining hampering inter ionic ito k1 kur mimic nak recordings rhythm sr trabeculae triangulation underlies variability yielding	anxa2 astrocytic astrocytoma bayesian blanket cd99 cdk4 col4a1 dramatically engineering glioblastoma hubs influential joint lifetime machine markov movement mpp2 multiforme network nfkbeta options rab31 seemed serbp1 top top2a validate
Tagcloud (Difference) ?		ap apd20 apd50 apd90 atrial caf cal calibrate calibrated determines deviating electrophysiology explaining hampering inter ionic ito k1 kur mimic nak recordings rhythm sr trabeculae triangulation underlies variability yielding	anxa2 astrocytic astrocytoma bayesian blanket cd99 cdk4 col4a1 dramatically engineering glioblastoma hubs influential joint lifetime machine markov movement mpp2 multiforme network nfkbeta options rab31 seemed serbp1 top top2a validate
Tagcloud (Intersection) ?