BTF3 and MED21

Number of citations of the paper that reports this interaction (PMID 2320128)
23

Data Source:
HPRD (in vitro)

		BTF3	MED21
Gene Name		basic transcription factor 3	mediator complex subunit 21
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Mediator Complex
	Molecular Function	Protein Binding Poly(A) RNA Binding	Transcription Coactivator Activity DNA-directed RNA Polymerase Activity Protein Binding
	Biological Process	In Utero Embryonic Development Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Protein Transport	Blastocyst Development Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Stem Cell Maintenance Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: APP CSNK2B ESR1 MED21 NACA POLR2B TXLNA TXLNB ZDHHC17	25 interactors: BLOC1S6 BRCA1 BTF3 CDK8 CDK9 ESR1 ESR2 HNF4A HTT MAGEB4 MED29 PCBD2 POLR2A SKP1 SSC5D TARBP2 TCEB3 TFG THRA THRB TP53 TRIM27 VAV2 ZNF655 ZSCAN1
Entrez ID		689	9412
HPRD ID		03966	09156
Ensembl ID		ENSG00000145741	ENSG00000152944
Uniprot IDs		P20290	F5H872 Q13503
PDB IDs		3LKX 3MCB
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Developmental Growth Cell Development Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Growth Positive Regulation Of Transcription, DNA-templated Synaptic Growth At Neuromuscular Junction Hormone-mediated Signaling Pathway Collateral Sprouting In Absence Of Injury Positive Regulation Of Skeletal Muscle Tissue Growth Prostate Epithelial Cord Elongation Developmental Growth Involved In Morphogenesis Regulation Of Cell Differentiation Stem Cell Maintenance Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Cell Differentiation Anatomical Structure Development Regulation Of Organ Morphogenesis Collateral Sprouting Axon Midline Choice Point Recognition Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway RNA Metabolic Process Intracellular Receptor Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Regulation Of Transcription From RNA Polymerase II Promoter Axon Choice Point Recognition Cell Differentiation Gene Expression DNA-templated Transcription, Initiation Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Developmental Process Adiponectin-activated Signaling Pathway Regulation Of Branching Involved In Prostate Gland Morphogenesis Mammary Gland Branching Involved In Pregnancy Cellular Macromolecule Biosynthetic Process Steroid Metabolic Process Stem Cell Development Neuron Remodeling Regulation Of Binding Macromolecule Biosynthetic Process	Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Regulation Of Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Organic Cyclic Compound RNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Viral Transcription Positive Regulation Of Gene Expression Gene Expression Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Nucleobase-containing Compound Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Cellular Biosynthetic Process Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Hormone-mediated Signaling Pathway Response To Steroid Hormone Regulation Of Viral Process Positive Regulation Of Metabolic Process Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Viral Process Response To Organic Cyclic Compound Positive Regulation Of Transcription, DNA-templated Cellular Response To Lipid Female Courtship Behavior Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Secretion Response To Stimulus Rhythmic Process Cellular Response To Stimulus Mating
Tagcloud ?		anxa2 astrocytic astrocytoma bayesian blanket cd99 cdk4 col4a1 dramatically engineering glioblastoma hubs influential joint lifetime machine markov movement mpp2 multiforme network nfkbeta options rab31 seemed serbp1 top top2a validate	accompanied beads blocking cadherin coactivator core defects differentiation drip drip205 facilitates glioma homolog hyperproliferation interacting keratinocyte keratinocytes med1 med10 mediator multisubunit newly oncogene promoting silencing subunit subunits vdr vitamin
Tagcloud (Difference) ?		anxa2 astrocytic astrocytoma bayesian blanket cd99 cdk4 col4a1 dramatically engineering glioblastoma hubs influential joint lifetime machine markov movement mpp2 multiforme network nfkbeta options rab31 seemed serbp1 top top2a validate	accompanied beads blocking cadherin coactivator core defects differentiation drip drip205 facilitates glioma homolog hyperproliferation interacting keratinocyte keratinocytes med1 med10 mediator multisubunit newly oncogene promoting silencing subunit subunits vdr vitamin
Tagcloud (Intersection) ?