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PPP1R12B and PRKG1
Number of citations of the paper that reports this interaction (PMID
10567269
)
92
Data Source:
BioGRID
(two hybrid)
PPP1R12B
PRKG1
Gene Name
protein phosphatase 1, regulatory subunit 12B
protein kinase, cGMP-dependent, type I
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Plasma Membrane
Molecular Function
Enzyme Activator Activity
CGMP-dependent Protein Kinase Activity
Calcium Channel Regulator Activity
Protein Binding
ATP Binding
CGMP Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Regulation Of Muscle Contraction
Signal Transduction
Positive Regulation Of Catalytic Activity
Neuron Migration
Protein Phosphorylation
Signal Transduction
Blood Coagulation
Dendrite Development
CGMP-mediated Signaling
Actin Cytoskeleton Organization
Forebrain Development
Regulation Of GTPase Activity
Relaxation Of Vascular Smooth Muscle
Negative Regulation Of Platelet Aggregation
Pathways
Ca2+ pathway
Signaling by Wnt
beta-catenin independent WNT signaling
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Asthma (
21907864
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
3 interactors:
IL16
PPP1CB
PRKG1
34 interactors:
ANXA7
CFTR
CREB1
CRIP2
FAM124A
FHOD1
GABRR1
GKAP1
GTF2I
HDAC1
ITPR1
LASP1
LMO2
MRVI1
NPR1
PDE5A
PLCB3
PPP1R12A
PPP1R12B
PPP1R17
PRKCA
RAF1
RGS2
RYR1
SELL
SEPT3
SF1
SPP1
TBXA2R
TNNT1
TRIM39-RPP21
TRPC3
VASP
ZNF646
Entrez ID
4660
5592
HPRD ID
04794
08910
Ensembl ID
ENSG00000077157
ENSG00000185532
Uniprot IDs
E1CKY7
O60237
Q13976
PDB IDs
1ZXA
3NMD
3OCP
3OD0
3OGJ
Enriched GO Terms of Interacting Partners
?
Regulation Of Glycogen Catabolic Process
Relaxation Of Vascular Smooth Muscle
CGMP-mediated Signaling
Relaxation Of Smooth Muscle
Negative Regulation Of Platelet Aggregation
Negative Regulation Of Smooth Muscle Contraction
Regulation Of Cell Adhesion
Regulation Of Platelet Aggregation
Induction Of Positive Chemotaxis
Negative Regulation Of Platelet Activation
Entrainment Of Circadian Clock By Photoperiod
Triglyceride Catabolic Process
Negative Regulation Of Muscle Contraction
Relaxation Of Muscle
Photoperiodism
Entrainment Of Circadian Clock
Acylglycerol Catabolic Process
Cell Migration
Regulation Of Glycogen Biosynthetic Process
Positive Regulation Of Positive Chemotaxis
Cyclic-nucleotide-mediated Signaling
Regulation Of Platelet Activation
Vasodilation
Cell Motility
Regulation Of Glycogen Metabolic Process
Regulation Of Smooth Muscle Contraction
Negative Regulation Of Blood Coagulation
Negative Regulation Of Coagulation
Glycogen Metabolic Process
Locomotion
Negative Regulation Of Wound Healing
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Generation Of Precursor Metabolites And Energy
Regulation Of Blood Vessel Size
Regulation Of Tube Size
Circadian Regulation Of Gene Expression
Polysaccharide Metabolic Process
Movement Of Cell Or Subcellular Component
Regulation Of Circadian Rhythm
Triglyceride Metabolic Process
Regulation Of Blood Coagulation
Regulation Of Glucose Metabolic Process
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Leukocyte Chemotaxis
Neutral Lipid Metabolic Process
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Chemotaxis
G2/M Transition Of Mitotic Cell Cycle
Regulation Of Body Fluid Levels
Hemostasis
Regulation Of Muscle Contraction
Blood Coagulation
Negative Regulation Of Muscle Contraction
Regulation Of Cardiac Muscle Hypertrophy
Wound Healing
Response To Wounding
Cellular Response To Stimulus
Response To Stimulus
Positive Regulation Of Cardiac Muscle Hypertrophy
Regulation Of Cellular Process
Response To Organic Substance
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Cellular Calcium Ion Homeostasis
Relaxation Of Muscle
Calcium Ion Homeostasis
Regulation Of Blood Vessel Size
Regulation Of Tube Size
Blood Circulation
Signal Transduction
Cellular Chemical Homeostasis
Regulation Of Phospholipase Activity
Platelet Activation
Ion Homeostasis
Neurotrophin TRK Receptor Signaling Pathway
Vasodilation
Neurotrophin Signaling Pathway
Cellular Metal Ion Homeostasis
Signaling
Cell Communication
Muscle System Process
Cellular Homeostasis
Metal Ion Homeostasis
Relaxation Of Vascular Smooth Muscle
Activation Of Phospholipase C Activity
Positive Regulation Of Metabolic Process
Regulation Of Smooth Muscle Contraction
Relaxation Of Smooth Muscle
Positive Regulation Of Phospholipase C Activity
Regulation Of Ion Homeostasis
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Response To Purine-containing Compound
Cytosolic Calcium Ion Homeostasis
Chemical Homeostasis
Cellular Response To Fibroblast Growth Factor Stimulus
Relaxation Of Cardiac Muscle
Tagcloud
?
1n9c
acsl3
agpat3
bovinesnp50
bta1
c10
c12
c14
c18
chuk
dgat1
echs1
ehhadh
groundwork
htr1b
lipj
lipk
minpp1
mogat1
nfkb2
osbpl8
oxct1
plink
scd1
sfa
sorbs1
ufa
underling
unraveling
Tagcloud (Difference)
?
1n9c
acsl3
agpat3
bovinesnp50
bta1
c10
c12
c14
c18
chuk
dgat1
echs1
ehhadh
groundwork
htr1b
lipj
lipk
minpp1
mogat1
nfkb2
osbpl8
oxct1
plink
scd1
sfa
sorbs1
ufa
underling
unraveling
Tagcloud (Intersection)
?