PPP1R12B and IL16

Number of citations of the paper that reports this interaction (PMID 12923170)
5

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		PPP1R12B	IL16
Gene Name		protein phosphatase 1, regulatory subunit 12B	interleukin 16
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Extracellular Space Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Enzyme Activator Activity	Cytokine Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Regulation Of Muscle Contraction Signal Transduction Positive Regulation Of Catalytic Activity	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Immune Response Viral Process Leukocyte Chemotaxis Induction Of Positive Chemotaxis
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Inattentive symptoms ( 18821565)
Protein-Protein Interactions		3 interactors: IL16 PPP1CB PRKG1	28 interactors: CASP3 CD4 CDK1 CSNK2A1 CSNK2A2 DMRTB1 EFEMP2 GABPB1 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 KCNA3 KCND1 KCND2 KCNJ1 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KDM1A PPP1R12A PPP1R12B PPP1R12C SSSCA1 SUV39H1 USHBP1
Entrez ID		4660	3603
HPRD ID		04794	04329
Ensembl ID		ENSG00000077157	ENSG00000172349
Uniprot IDs		E1CKY7 O60237	Q14005 Q9UME6
PDB IDs			1I16 1X6D
Enriched GO Terms of Interacting Partners?		Regulation Of Glycogen Catabolic Process Relaxation Of Vascular Smooth Muscle CGMP-mediated Signaling Relaxation Of Smooth Muscle Negative Regulation Of Platelet Aggregation Negative Regulation Of Smooth Muscle Contraction Regulation Of Cell Adhesion Regulation Of Platelet Aggregation Induction Of Positive Chemotaxis Negative Regulation Of Platelet Activation Entrainment Of Circadian Clock By Photoperiod Triglyceride Catabolic Process Negative Regulation Of Muscle Contraction Relaxation Of Muscle Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Cell Migration Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Positive Chemotaxis Cyclic-nucleotide-mediated Signaling Regulation Of Platelet Activation Vasodilation Cell Motility Regulation Of Glycogen Metabolic Process Regulation Of Smooth Muscle Contraction Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Glycogen Metabolic Process Locomotion Negative Regulation Of Wound Healing Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Blood Vessel Size Regulation Of Tube Size Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Movement Of Cell Or Subcellular Component Regulation Of Circadian Rhythm Triglyceride Metabolic Process Regulation Of Blood Coagulation Regulation Of Glucose Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Leukocyte Chemotaxis Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Chemotaxis G2/M Transition Of Mitotic Cell Cycle	Synaptic Transmission Potassium Ion Transmembrane Transport Potassium Ion Transport Potassium Ion Import Cell-cell Signaling Cation Transmembrane Transport Signaling Cell Communication Ion Transmembrane Transport Metal Ion Transport Regulation Of Ion Transmembrane Transport Cation Transport Transmembrane Transport Ion Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Ion Transport Monovalent Inorganic Cation Transport Regulation Of Membrane Potential Regulation Of Cellular Process Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Regulation Of Sensory Perception Of Pain Startle Response Directional Locomotion Protein Homooligomerization Membrane Depolarization Negative Regulation Of Protein Catabolic Process Neuromuscular Process Regulation Of Resting Membrane Potential Regulation Of Neurological System Process Regulation Of Protein Catabolic Process Cell Cycle Regulation Of Excitatory Postsynaptic Membrane Potential Mitotic Cell Cycle Process Regulation Of Postsynaptic Membrane Potential Response To Wounding Protein Complex Assembly Cell Cycle Process Protein Oligomerization Negative Regulation Of Cell Cycle Potassium Ion Homeostasis Mitotic Cell Cycle Negative Regulation Of Chromosome Organization Locomotion G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Process Response To External Stimulus
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