COX1 and MEOX2

Number of citations of the paper that reports this interaction (PMID 16335786)
1

Data Source:
BioGRID (two hybrid)

		COX1	MEOX2
Gene Name		cytochrome c oxidase subunit I	mesenchyme homeobox 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Nuclear Speck
	Molecular Function		RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process		Angiogenesis Somite Specification Transcription, DNA-templated Multicellular Organismal Development Skeletal Muscle Tissue Development Blood Circulation Positive Regulation Of Transcription From RNA Polymerase II Promoter Palate Development Limb Development Neuron Death
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport Orphan transporters
Drugs
Diseases
GWAS			Blood trace element (Zn levels) ( 23720494)
Protein-Protein Interactions		9 interactors: CDC42 CLEC4G COX4I1 COX5A KCNMB1 LIG4 MEOX2 PRDX4 SNCA	207 interactors: ADAMTS12 AGPAT1 AHCYL1 AHSA2 ANP32B ARHGEF7 ARNT2 ATG5 ATXN1L BCL2L15 C19orf66 C1orf109 CARD9 CASP14 CCDC103 CCNC CDH9 CEP57L1 CHIC2 CHRD CIAPIN1 CIB3 CNTNAP2 COX1 CPNE6 CPSF4 CRCT1 CSDC2 CSF2 CTNNBL1 CXXC1 DGCR6 DGCR8 DOCK8 DYNLL2 EDF1 EFEMP2 EFNA3 EIF1AD EIF5A EPM2AIP1 ESR2 ESRRG FAM13C FAM3A FAM74A4 FBF1 FOXR1 FUCA2 FUT11 GABRB3 GAGE1 GLO1 GMCL1P1 GMPR2 GNG11 GOLGA8DP GOLGA8EP GOLGA8F GPATCH2L GPSM3 HAT1 HDHD2 HEXIM2 HGF HLA-A HNRNPD HP1BP3 HSPA2 HTR1E IGF2BP3 IGFN1 INPP1 IP6K2 ITM2A KAT5 KIZ KLC4 KLHL38 KRT80 KRT86 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KTN1 LAMTOR5 LCE1B LCE2A LCE4A LOC153684 LSM2 MAGED1 MAPKBP1 MKRN3 MLLT6 MMP3 MORN3 MRFAP1L1 MSI2 MT1DP MTMR10 MUM1 MVP MYBPC1 NAA10 NALCN NCALD NCK2 ND1 NLGN3 NTF3 OIT3 OSGIN1 P4HA3 PACSIN2 PAGE2 PARK2 PARVG PAX1 PAX3 PCDH9 PCSK5 PGBD1 PIN1 PKIG POM121C PRKAB2 PRR19 PSMB10 PSMC1 PSMD14 PTGER3 RARB RCHY1 RECK RHOJ RMND5A RND2 RPL15 RUNX1T1 SAMM50 SCNM1 SEPP1 SET SIRPB1 SLC48A1 SMAD3 SMARCE1 SPATA1 SPP1 SPRY1 SPRY2 SSX3 STK16 STX11 STX16 SYT17 TBCEL TBX6 TCEA2 TCL6 TCTEX1D1 TDO2 TGFB1 TICAM2 TMEM100 TP53BP1 TRAF6 TRIM41 TRIM42 TTC25 TTC39B TTC9C TULP2 TXLNA UBE3A UBL4A UBL4B UNC45A USE1 VEZF1 VIP WFDC9 XRCC2 ZBED4 ZMAT2 ZNF124 ZNF329 ZNF404 ZNF417 ZNF483 ZNF564 ZNF572 ZNF587 ZNF695
Entrez ID		4512	4223
HPRD ID		02469	02760
Ensembl ID			ENSG00000106511
Uniprot IDs		P00395 Q7GXY8	P50222
PDB IDs
Enriched GO Terms of Interacting Partners?		Respiratory Electron Transport Chain Electron Transport Chain Cellular Respiration Monovalent Inorganic Cation Transport Regulation Of Neuron Apoptotic Process Regulation Of Neuron Death Energy Derivation By Oxidation Of Organic Compounds Response To Metal Ion Neuron Death Generation Of Precursor Metabolites And Energy Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Male Germ Cell Proliferation DNA Ligation Involved In DNA Recombination Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Cation Transport Response To Inorganic Substance Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hair Follicle Cell Proliferation Cellular Response To Metal Ion Negative Regulation Of Protein Complex Assembly Oxidation-reduction Process Regulation Of Protein Stability Cellular Response To Inorganic Substance Regulation Of Male Germ Cell Proliferation Negative Regulation Of Dopamine Metabolic Process Submandibular Salivary Gland Formation Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Actin Filament Branching Negative Regulation Of Cellular Respiration Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Phosphorylation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Regulation Of Microtubule-based Process Negative Regulation Of Neuron Apoptotic Process Hydrogen Ion Transmembrane Transport Ion Transport Lagging Strand Elongation Pro-B Cell Differentiation Establishment Of Golgi Localization Response To Iron(II) Ion Cellular Response To Copper Ion Somite Specification	Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cell Death Anatomical Structure Development Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Epithelium Development Positive Regulation Of Gene Expression Developmental Process Regulation Of Transcription, DNA-templated Cellular Response To Organic Substance RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Cell Death Regulation Of RNA Biosynthetic Process Response To Organic Substance Positive Regulation Of Transcription, DNA-templated Death Apoptotic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Process Positive Regulation Of DNA Binding RNA Metabolic Process System Development Regulation Of Protein Ubiquitination Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of DNA Binding Myeloid Dendritic Cell Differentiation Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Metabolic Process Multicellular Organismal Development Positive Regulation Of Protein Ubiquitination Myeloid Dendritic Cell Activation
Tagcloud ?		adipogenic assessments cd105 cd73 cd90 chondrogenic derangement fetal galactosidase gdm gestation gestational huc immunoblotting intriguing jelly msc mscs nd2 nd9 osteogenic pgc programming senescence tfam uc umbilical underscore wharton	activates angiogenic biphasic colocalization colocalizes constructs depend ec ecs homeobox homeodomain homeoprotein hypothesize ikappabbeta immunofluorescence implicate ingrowth modulate modulates normally p65 proangiogenic promoters rela represses secrete stimulates transduced vessels
Tagcloud (Difference) ?		adipogenic assessments cd105 cd73 cd90 chondrogenic derangement fetal galactosidase gdm gestation gestational huc immunoblotting intriguing jelly msc mscs nd2 nd9 osteogenic pgc programming senescence tfam uc umbilical underscore wharton	activates angiogenic biphasic colocalization colocalizes constructs depend ec ecs homeobox homeodomain homeoprotein hypothesize ikappabbeta immunofluorescence implicate ingrowth modulate modulates normally p65 proangiogenic promoters rela represses secrete stimulates transduced vessels
Tagcloud (Intersection) ?