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MSH3 and RPA4
Number of citations of the paper that reports this interaction (PMID
19468048
)
25
Data Source:
BioGRID
(pull down)
MSH3
RPA4
Gene Name
mutS homolog 3
replication protein A4, 30kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Chromosome
Nucleus
Nucleoplasm
Membrane
MutSbeta Complex
Nucleus
Nucleoplasm
DNA Replication Factor A Complex
Molecular Function
Y-form DNA Binding
Heteroduplex DNA Loop Binding
Double-strand/single-strand DNA Junction Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
Centromeric DNA Binding
Enzyme Binding
Mismatched DNA Binding
Guanine/thymine Mispair Binding
Dinucleotide Insertion Or Deletion Binding
Single Guanine Insertion Binding
Dinucleotide Repeat Insertion Binding
Oxidized Purine DNA Binding
Protein Homodimerization Activity
Single-stranded DNA Binding
Biological Process
Meiotic Mismatch Repair
DNA Repair
Mismatch Repair
Reciprocal Meiotic Recombination
Somatic Recombination Of Immunoglobulin Gene Segments
Maintenance Of DNA Repeat Elements
Negative Regulation Of DNA Recombination
Positive Regulation Of Helicase Activity
DNA Damage Checkpoint
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication Initiation
Nucleotide-excision Repair
DNA Recombination
Nuclear DNA Replication
Pathways
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Mismatch Repair
G1/S Transition
Activation of the pre-replicative complex
DNA Replication Pre-Initiation
M/G1 Transition
Activation of the pre-replicative complex
Mitotic G1-G1/S phases
Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
BARD1
BRCA1
EXO1
HUS1
MLH1
MSH2
PCNA
RAD1
RAD9A
RCHY1
RPA4
XPA
7 interactors:
APP
MSH2
MSH3
MUTYH
RPA1
RPA3
XPA
Entrez ID
4437
29935
HPRD ID
02931
06591
Ensembl ID
ENSG00000113318
ENSG00000204086
Uniprot IDs
A1L480
P20585
Q13156
PDB IDs
3THW
3THX
3THY
3THZ
Enriched GO Terms of Interacting Partners
?
DNA Repair
Cellular Response To DNA Damage Stimulus
DNA Metabolic Process
Cellular Response To Stress
DNA Recombination
Cell Cycle
DNA Damage Checkpoint
Cell Cycle Process
Cell Cycle Checkpoint
DNA Replication
Response To Ionizing Radiation
Response To Stress
Mismatch Repair
Somatic Hypermutation Of Immunoglobulin Genes
Somatic Diversification Of Immune Receptors Via Somatic Mutation
Response To Radiation
Negative Regulation Of Cell Cycle
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Nucleobase-containing Compound Metabolic Process
Postreplication Repair
Isotype Switching
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Somatic Recombination Of Immunoglobulin Gene Segments
DNA Catabolic Process
DNA Catabolic Process, Exonucleolytic
Double-strand Break Repair
Somatic Diversification Of Immunoglobulins
Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response
Nitrogen Compound Metabolic Process
B Cell Activation Involved In Immune Response
Cellular Macromolecule Catabolic Process
Aromatic Compound Catabolic Process
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cell Cycle
Meiotic Cell Cycle
Cellular Response To Ionizing Radiation
Immunoglobulin Production
Protein K6-linked Ubiquitination
Response To Abiotic Stimulus
Cellular Response To Stimulus
Intra-S DNA Damage Checkpoint
Mitotic Cell Cycle Process
Nucleotide-excision Repair
Negative Regulation Of DNA Metabolic Process
Apoptotic Signaling Pathway
Mitotic Cell Cycle
Response To UV
Cellular Metabolic Process
Mismatch Repair
DNA Repair
Nucleotide-excision Repair, DNA Damage Removal
Cellular Response To DNA Damage Stimulus
DNA Catabolic Process
DNA Metabolic Process
Meiotic Mismatch Repair
DNA Recombination
Maintenance Of DNA Repeat Elements
Cellular Response To Stress
Base-excision Repair
DNA Recombinase Assembly
Positive Regulation Of Helicase Activity
Response To Stress
Nucleotide-excision Repair
Response To Abiotic Stimulus
Aromatic Compound Catabolic Process
Double-strand Break Repair
Nucleotide-excision Repair, DNA Gap Filling
Nucleobase-containing Compound Metabolic Process
Meiotic Nuclear Division
Telomere Maintenance Via Semi-conservative Replication
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of DNA Recombination
Nuclear DNA Replication
Telomere Maintenance Via Recombination
Cellular Nitrogen Compound Metabolic Process
Meiotic Cell Cycle
Mitotic Recombination
DNA Strand Elongation Involved In DNA Replication
Regulation Of Cellular Response To Heat
DNA Strand Elongation
Telomere Maintenance Via Telomere Lengthening
Nitrogen Compound Metabolic Process
Somatic Recombination Of Immunoglobulin Gene Segments
Somatic Diversification Of Immunoglobulins
Cellular Macromolecule Catabolic Process
Transcription-coupled Nucleotide-excision Repair
Response To Light Stimulus
Chromosome Organization
Reproduction
Cell Cycle Process
Cellular Response To Stimulus
Immunoglobulin Production
Cellular Response To Heat
Regulation Of DNA Recombination
Regulation Of Mitotic Cell Cycle
Telomere Maintenance
Response To Radiation
Tagcloud
?
addressed
aom
apc
apex1
azoxymethane
carcinogenesis
colorectal
crc
dextran
dss
epi
experimentally
expressions
mgmt
mismatch
mlh1
mlh3
mmr
pilot
pms1
pms2
precancerous
prerequisite
rectum
sacrificed
sequential
sigmoid
sulphate
suppressor
Tagcloud (Difference)
?
addressed
aom
apc
apex1
azoxymethane
carcinogenesis
colorectal
crc
dextran
dss
epi
experimentally
expressions
mgmt
mismatch
mlh1
mlh3
mmr
pilot
pms1
pms2
precancerous
prerequisite
rectum
sacrificed
sequential
sigmoid
sulphate
suppressor
Tagcloud (Intersection)
?