MICOS10 and CIDEB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MICOS10	CIDEB
Description		mitochondrial contact site and cristae organizing system subunit 10	cell death inducing DFFA like effector b
Image		No pdb structure
GO Annotations	Cellular Component	SAM Complex Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Crista Junction MICOS Complex MIB Complex	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane COPII Vesicle Coat COPI-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Molecular Adaptor Activity Phosphatidic Acid Binding Lipid Transfer Activity
	Biological Process	Inner Mitochondrial Membrane Organization Cristae Formation	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Lipid Storage Response To Nutrient Levels Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Apoptotic Process COPII-coated Vesicle Cargo Loading Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion
Pathways		Cristae formation
Drugs
Diseases
GWAS			Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		4 interacting genes: APOC2 APOC4 CIDEB MPC2	68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C IRX2-DT MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1
Entrez ID		440574	27141
HPRD ID		18824	11981
Ensembl ID		ENSG00000173436	ENSG00000136305
Uniprot IDs		A0A087WU07 Q5TGZ0	Q9UHD4
PDB IDs			1D4B
Enriched GO Terms of Interacting Partners?		Acylglycerol Homeostasis High-density Lipoprotein Particle Lipid Transport Very-low-density Lipoprotein Particle Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Lipid Storage Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Pyruvate Import Into Mitochondria Lipid Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remodeling Positive Regulation Of Phospholipid Catabolic Process Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Intermediate-density Lipoprotein Particle Lipoprotein Lipase Activator Activity Pyruvate Transmembrane Transport Pyruvate Transmembrane Transporter Activity Inner Mitochondrial Membrane Protein Complex Lipid Droplet Fusion Spherical High-density Lipoprotein Particle Positive Regulation Of Triglyceride Catabolic Process Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Very-low-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Clearance Pyruvate Transport Import Into The Mitochondrion Pyruvate Decarboxylation To Acetyl-CoA Regulation Of Lipid Metabolic Process Triglyceride-rich Lipoprotein Particle Remodeling Phospholipase Activator Activity Very-low-density Lipoprotein Particle Assembly Lipoprotein Catabolic Process Chylomicron Phospholipid Efflux Lipid Transfer Activity Acetyl-CoA Biosynthetic Process COPI-coated Vesicle Low-density Lipoprotein Particle COPII Vesicle Coat Reverse Cholesterol Transport Identical Protein Binding Negative Regulation Of Lipoprotein Particle Clearance COPII-coated Vesicle Cargo Loading Phospholipase Binding Negative Regulation Of Cholesterol Transport Mitochondrial Transmembrane Transport Positive Regulation Of Triglyceride Metabolic Process	Mitochondrion Mitochondrial Inner Membrane Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Apoptotic DNA Fragmentation High-density Lipoprotein Particle Protein Binding Mitochondrion Organization Mitochondrial Membrane Copper Chaperone Activity Disordered Domain Specific Binding T Cell Apoptotic Process Mitochondrial Matrix Organophosphate Biosynthetic Process Cytochrome Complex Assembly Pyruvate Decarboxylation To Acetyl-CoA Activation-induced Cell Death Of T Cells Mitochondrial Respiratory Chain Complex Assembly Lymphocyte Apoptotic Process Import Into The Mitochondrion Negative Regulation Of Execution Phase Of Apoptosis Protein Localization To Mitochondrion
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