ASNS and TRIM69

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ASNS	TRIM69
Gene Name		asparagine synthetase (glutamine-hydrolyzing)	tripartite motif containing 69
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Plasma Membrane Nuclear Speck
	Molecular Function	Asparagine Synthase (glutamine-hydrolyzing) Activity ATP Binding Protein Homodimerization Activity Cofactor Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Liver Development Asparagine Biosynthetic Process Glutamine Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Cellular Amino Acid Biosynthetic Process Response To Light Stimulus Response To Mechanical Stimulus Response To Toxic Substance Endoplasmic Reticulum Unfolded Protein Response Response To Methotrexate Response To Follicle-stimulating Hormone Cellular Response To Hormone Stimulus Cellular Nitrogen Compound Metabolic Process Cellular Response To Glucose Starvation Negative Regulation Of Apoptotic Process Response To Amino Acid Cellular Protein Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Mitotic Cell Cycle L-asparagine Biosynthetic Process	Apoptotic Process Protein Ubiquitination
Pathways		Amino acid synthesis and interconversion (transamination) ATF4 activates genes PERK regulates gene expression Unfolded Protein Response (UPR) Metabolism of amino acids and derivatives
Drugs		L-Aspartic Acid L-Glutamic Acid Adenosine triphosphate L-Asparagine
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ATXN1 STRN4 TRIM69 WDR27	22 interactors: APP ASNS ATP5G1 DVL1 FAM110A FKBP1B HAUS1 IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 ZNF483
Entrez ID		440	140691
HPRD ID		00153	11518
Ensembl ID		ENSG00000070669	ENSG00000185880
Uniprot IDs		P08243	Q86WT6
PDB IDs
Enriched GO Terms of Interacting Partners?			MRNA 3'-splice Site Recognition Collateral Sprouting Maintenance Of Protein Location In Nucleus Anatomical Structure Development System Development Negative Regulation Of Catalytic Activity Protein Localization To Nucleus Regulation Of Cell Development Developmental Process Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Cell Development Morphogenesis Of An Epithelium MRNA Splice Site Selection Multicellular Organismal Development Organ Development Positive Regulation Of Neuron Projection Development Regulation Of Neuron Differentiation Neuromuscular Junction Development Cellular Nitrogen Compound Metabolic Process Epithelium Development Negative Regulation Of Translation In Response To Oxidative Stress L-asparagine Biosynthetic Process Regulation Of Hormone Levels Anatomical Structure Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Tissue Development Regulation Of Translation Spliceosomal Complex Assembly Positive Regulation Of Cell Projection Organization Tissue Morphogenesis Positive Regulation Of Cell Cycle Regulation Of Proteolysis Cellular Calcium Ion Homeostasis Positive Regulation Of Proteolysis Cell Differentiation Calcium Ion Homeostasis Regulation Of Neurogenesis Positive Regulation Of Protein Metabolic Process Gene Expression Cellular Component Assembly Regulation Of Calcium Ion Transport Into Cytosol Synaptic Growth At Neuromuscular Junction Positive Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Neuron Differentiation Nitrogen Compound Metabolic Process Response To Light Stimulus Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		accordingly alters asparagine atf4 captures connection delivers extracellularly gas hemolysin inflict internalized irreversible multiplication nutrients obviating pathogens poorly senses slo sls streptococcus streptolysin synthetase toxins trigger unfolded upr
Tagcloud (Difference) ?		accordingly alters asparagine atf4 captures connection delivers extracellularly gas hemolysin inflict internalized irreversible multiplication nutrients obviating pathogens poorly senses slo sls streptococcus streptolysin synthetase toxins trigger unfolded upr
Tagcloud (Intersection) ?