MPG and RAD23A

Number of citations of the paper that reports this interaction (PubMedID 10854423)
0

Data Source:
HPRD (in vitro)

		MPG	RAD23A
Description		N-methylpurine DNA glycosylase	RAD23 nucleotide excision repair protein A
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Mitochondrial Nucleoid	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Protein-containing Complex
	Molecular Function	DNA Binding Damaged DNA Binding Catalytic Activity Alkylbase DNA N-glycosylase Activity Protein Binding Hydrolase Activity DNA N-glycosylase Activity	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Kinase Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding Ubiquitin-specific Protease Binding
	Biological Process	DNA Repair Base-excision Repair DNA Alkylation Repair DNA Damage Response Depurination	DNA Repair Nucleotide-excision Repair DNA Damage Response Protein Destabilization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Cell Cycle
Pathways		Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Displacement of DNA glycosylase by APEX1	Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER
Drugs		Cisplatin Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576) Glioblastoma ( 28346443) Hemoglobin levels ( 26366553) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell traits ( 23446634)	Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		13 interacting genes: ACKR5 APP CRK EP300 ESR1 FBXO7 HSD17B14 MLH1 RAD23A RAD23B RXRA TERF2IP THRB	79 interacting genes: A2M ADRM1 ANKRD40 ATXN3 ATXN7 CCNA2 CDC37 CEBPA CHEK1 CNTROB CREBBP DAZAP2 DBI ECSIT EP300 EWSR1 FILIP1 GTF2H1 H4C1 HSPB1 IFIT3 IFIT5 KRTAP12-2 LOXL4 MAP3K1 MAST1 MDM2 MINDY3 MKRN1 MPG NEDD8 NGLY1 NUTM2F OGT PDE6D PHAX PI4K2A PRKN PSEN1 PSMC5 PSMD4 RABGEF1 REL RNF115 RNF32 RNF41 RPN1 RPS27A SH3RF1 SMURF1 SQSTM1 TNFAIP3 TRAF2 TRAF3 TRAF5 TRAF6 TRIM39 TRIM50 TRIM54 TRIM55 TRIM8 TRIP6 UBA52 UBB UBC UBE3A UBE4B UBL7 UBQLN4 UBXN1 UIMC1 USP25 VAV2 WWP2 XPC ZBTB26 ZBTB44 ZBTB8A ZFAND6
Entrez ID		4350	5886
HPRD ID		06766	07191
Ensembl ID		ENSG00000103152	ENSG00000179262
Uniprot IDs		P29372 Q1W6H1	A8K1J3 P54725
PDB IDs		1BNK 1EWN 1F4R 1F6O 3QI5 3UBY 7XFH 7XFJ 7XFM	1DV0 1F4I 1IFY 1OQY 1P98 1P9D 1QZE 1TP4 2WYQ 5XBO 6W2G 6W2H 6W2I 6XQI 6XQJ 7TGP 8Q06
Enriched GO Terms of Interacting Partners?		Enzyme Binding Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Nucleic Acid Metabolic Process Transcription Coregulator Binding Transcription Coactivator Binding Nuclear Receptor Activity Regulation Of Thyroid Hormone Receptor Signaling Pathway Protein-containing Complex Damaged DNA Binding Chromatin Binding Cell Development Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Signal Transduction Response To Yeast Transcription By RNA Polymerase II Nuclear Receptor-mediated Signaling Pathway Ubiquitin Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Localization To Chromosome Single-stranded DNA Binding Positive Regulation Of DNA-binding Transcription Factor Activity Proteasome Binding Mating Behavior Macromolecule Metabolic Process Regulation Of Metabolic Process Nuclear Steroid Receptor Activity Regulation Of Primary Metabolic Process Positive Regulation Of Intracellular Signal Transduction Retinoic Acid Receptor Signaling Pathway Negative Regulation Of MiRNA Transcription Intracellular Signal Transduction Ephrin Receptor Binding Hormone-mediated Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Nucleus DNA Damage Response DNA-templated Transcription Reproductive Behavior Positive Regulation Of Protein Localization Regulation Of Innate Immune Response Catabolic Process Positive Regulation Of Metabolic Process Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Macromolecule Metabolic Process Polyubiquitin Modification-dependent Protein Binding Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process	Post-translational Protein Modification Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification Process Protein Modification By Small Protein Conjugation Cytosol Protein Polyubiquitination Protein Autoubiquitination Modification-dependent Protein Catabolic Process Regulation Of Proteolysis Protein Metabolic Process Proteolysis Involved In Protein Catabolic Process Ubiquitin Protein Ligase Binding Regulation Of Proteasomal Protein Catabolic Process Proteolysis Macromolecule Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Zinc Ion Binding Regulation Of Protein Metabolic Process Protein K63-linked Ubiquitination Ubiquitin-protein Transferase Activity Cytoplasm Regulation Of Canonical NF-kappaB Signal Transduction Ubiquitin-dependent Protein Catabolic Process Protein Tag Activity Macromolecule Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Protein Catabolic Process Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Regulation Of Signal Transduction Protein K48-linked Deubiquitination CD40 Receptor Complex Transferase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Catabolic Process Canonical NF-kappaB Signal Transduction Positive Regulation Of Proteolysis Ubiquitin Binding Positive Regulation Of Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Immune Response-regulating Cell Surface Receptor Signaling Pathway Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding Protein Binding Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Signaling
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