MPG and RAD23A

Number of citations of the paper that reports this interaction (PMID 10854423)
26

Data Source:
HPRD (in vitro)

		MPG	RAD23A
Gene Name		N-methylpurine-DNA glycosylase	RAD23 homolog A (S. cerevisiae)
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrial Nucleoid	Proteasome Complex Nucleoplasm Cytoplasm
	Molecular Function	Damaged DNA Binding Alkylbase DNA N-glycosylase Activity Protein Binding DNA-3-methyladenine Glycosylase Activity DNA-7-methylguanine Glycosylase Activity DNA-7-methyladenine Glycosylase Activity DNA-3-methylguanine Glycosylase Activity	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Binding Ubiquitin-specific Protease Binding
	Biological Process	DNA Repair Base-excision Repair Base-excision Repair, AP Site Formation DNA Dealkylation Involved In DNA Repair Depurination	Nucleotide-excision Repair Viral Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication
Pathways		Depurination Base Excision Repair Resolution of AP sites via the multiple-nucleotide patch replacement pathway Base-Excision Repair, AP Site Formation Removal of DNA patch containing abasic residue Resolution of AP sites via the single-nucleotide replacement pathway Base-free sugar-phosphate removal via the single-nucleotide replacement pathway Displacement of DNA glycosylase by APE1 Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Resolution of Abasic Sites (AP sites)
Drugs
Diseases
GWAS		Red blood cell traits ( 23446634)
Protein-Protein Interactions		9 interactors: APP EP300 ESR1 HSD17B14 RAD23A RAD23B RXRA TERF2IP THRB	50 interactors: A2M ADRM1 ANKRD40 ATXN3 ATXN7 CCNA2 CCNB1 CDC37 CREBBP DBI ECSIT EP300 EWSR1 FAM188A FILIP1 GTF2H1 IFIT3 IFIT5 LOXL4 MAST1 MDM2 MPG NGLY1 PARK2 PDE6D PHAX PI4K2A PSEN1 PSMC5 PSMD4 RNF115 RNF32 RPN1 SQSTM1 TRAF2 TRAF5 TRIM54 TRIP6 UBB UBE2D1 UBE2L3 UBE2L6 UBE3A UBL7 UBQLN4 USP25 VAV2 XPC ZBTB44 ZBTB8A
Entrez ID		4350	5886
HPRD ID		06766	07191
Ensembl ID		ENSG00000103152	ENSG00000179262
Uniprot IDs		P29372 Q1W6H1	A8K1J3 P54725
PDB IDs		1BNK 1EWN 1F4R 1F6O 3QI5 3UBY	1DV0 1F4I 1IFY 1OQY 1P98 1P9D 1QZE 1TP4 1ZO6 2WYQ
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Steroid Metabolic Process Regulation Of Branching Involved In Prostate Gland Morphogenesis Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Reproduction Response To Steroid Hormone Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Cellular Response To Steroid Hormone Stimulus Mating Behavior Reproductive Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Multicellular Organismal Reproductive Process Mating Multicellular Organism Reproduction Response To Lipid Cellular Response To DNA Damage Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Organic Cyclic Compound Cellular Response To Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Response To Hormone Regulation Of Morphogenesis Of A Branching Structure Prostate Gland Development Positive Regulation Of Viral Process Organ Morphogenesis RNA Metabolic Process Cellular Response To Organic Cyclic Compound Chromosome Organization Regulation Of Cellular Protein Metabolic Process Histone H2B Acetylation Negative Regulation Of DNA Recombination At Telomere Maternal Process Involved In Female Pregnancy Cellular Response To Lipid Epithelium Development Negative Regulation Of Cellular Metabolic Process Gene Expression Posttranscriptional Regulation Of Gene Expression	Cellular Macromolecule Catabolic Process Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Catabolic Process Protein Polyubiquitination Regulation Of Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Metabolic Process Cellular Response To Stress Response To Stress Cellular Protein Modification Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Ubiquitination Positive Regulation Of Ligase Activity Positive Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Checkpoint Mitotic DNA Damage Checkpoint Proteasomal Protein Catabolic Process Cell Cycle Phase Transition Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Mitotic DNA Integrity Checkpoint Cellular Response To Oxygen Levels Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Catalytic Activity Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Cellular Protein Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle Phase Transition Innate Immune Response
Tagcloud ?		adherens arg1 cadherin cadherins clustered coculture coculturing coimmunoprecipitation csi desmocollin desmoglein desmoplakin desmosomal desmosomes dsc dsc1 dsc1a dsg dsg2 fibrosarcoma ht intercellular junctions lysates plakoglobin portion repeats tagged thr170	2h5 accompanies anova dynactin gadd45a gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Difference) ?		adherens arg1 cadherin cadherins clustered coculture coculturing coimmunoprecipitation csi desmocollin desmoglein desmoplakin desmosomal desmosomes dsc dsc1 dsc1a dsg dsg2 fibrosarcoma ht intercellular junctions lysates plakoglobin portion repeats tagged thr170	2h5 accompanies anova dynactin gadd45a gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Intersection) ?