MLLT6 and TCF12

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MLLT6	TCF12
Gene Name		myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	transcription factor 12
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nuclear Chromatin Nucleus Cytoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	Protein Binding Zinc Ion Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Enhancer Binding BHLH Transcription Factor Binding Transcription Regulatory Region DNA Binding SMAD Binding Protein Heterodimerization Activity E-box Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Immune Response Muscle Organ Development Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: APP CASK CEBPE CEBPG CEP44 CRX DOT1L ENOX2 IKBKG KRTAP10-8 MED15 MEOX2 SPRY2 TCF12 TCF4 UBE2G2 UBQLN1 UBQLN4 WHSC1L1 ZBTB22	48 interactors: ARMC8 ASCL4 BMF C16orf45 C1orf109 C6orf165 CDKN2C CRCP CREBBP DGCR6 EDRF1 EP300 HAND1 HEXIM2 HOPX ID1 ID2 ID3 LYSMD1 MAPKBP1 MLLT6 MORN4 MSC NAGK NEUROG3 OLIG3 OSGIN1 PRSS23 PSMA1 PTF1A QARS RNASEL RUNX1T1 SOX10 SOX8 SPG21 SRI STAT5A STK16 TAF4 TAL2 TBP TCF23 TCF3 TRIM72 TSNAX TWIST2 VPS28
Entrez ID		4302	6938
HPRD ID		08978	02725
Ensembl ID		ENSG00000108292	ENSG00000140262
Uniprot IDs		P55198	B4E1W1 F5GY10 Q99081
PDB IDs			2KNH 4JOL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Binding Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Nitrogen Compound Metabolic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Organ Development Biosynthetic Process Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Growth Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Neuron Differentiation Regulation Of Cellular Process Regulation Of Protein Metabolic Process Ultradian Rhythm Histone H3-K79 Methylation Positive Regulation Of Photoreceptor Cell Differentiation Anatomical Structure Development Neuron Death Regulation Of Epidermal Growth Factor Receptor Signaling Pathway System Development Regulation Of Neurogenesis Synaptic Growth At Neuromuscular Junction Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition	Gene Expression Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Organ Development Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process System Development Transcription From RNA Polymerase II Promoter Biosynthetic Process Anatomical Structure Development Regulation Of DNA Binding Regulation Of Binding Negative Regulation Of DNA Binding Positive Regulation Of Transcription, DNA-templated Muscle Organ Development Central Nervous System Development Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Muscle Structure Development Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Binding Rhythmic Process Regulation Of Cellular Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?		abl1 aff1 cbfb cryptic cytogenetics dek ell etv6 fifteen inv mllt1 mllt10 mllt3 mllt4 mrt multiplex myh11 nup214 p13 pbx1 q23 rara runx1 runx1t1 simplified tcf3 translocations zbtb16	cadherin cascade cd91 connexin consistently crc drastically ectopic efficiently enhancement facilitated fibronectin gap hsp90alpha ikappabalpha ikkalpha ikks invasion junction knocked mesenchymal migration motifs outgrowths repressed rhsp90alpha secreted spherical spreading
Tagcloud (Difference) ?		abl1 aff1 cbfb cryptic cytogenetics dek ell etv6 fifteen inv mllt1 mllt10 mllt3 mllt4 mrt multiplex myh11 nup214 p13 pbx1 q23 rara runx1 runx1t1 simplified tcf3 translocations zbtb16	cadherin cascade cd91 connexin consistently crc drastically ectopic efficiently enhancement facilitated fibronectin gap hsp90alpha ikappabalpha ikkalpha ikks invasion junction knocked mesenchymal migration motifs outgrowths repressed rhsp90alpha secreted spherical spreading
Tagcloud (Intersection) ?