MLLT6 and ENOX2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		MLLT6	ENOX2
Description		MLLT6, PHD finger containing	ecto-NOX disulfide-thiol exchanger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Cytosol Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Nucleosome Binding Histone Binding Metal Ion Binding	Nucleic Acid Binding RNA Binding Protein Binding Oxidoreductase Activity
	Biological Process	Renal System Process Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Sodium Ion Transport Negative Regulation Of Urine Volume Renal Sodium Excretion Renal Potassium Excretion Positive Regulation Of Transcription By RNA Polymerase II Renal Water Absorption	Ultradian Rhythm Electron Transport Chain Rhythmic Process
Pathways
Drugs			Idronoxil
Diseases
GWAS			Hemoglobin ( 32888494)
Interacting Genes		26 interacting genes: APP CASK CEBPE CEBPG CEP44 CREB5 CRX ENOX2 EPS15 GRIPAP1 IKBKG KRTAP10-8 MED15 MEOX2 NSD3 PHC2 PIN1 SPRY2 TCF12 TCF4 TLE5 UBE2G2 UBQLN1 UBQLN4 ZBTB22 ZMYND19	19 interacting genes: CDC37 CIB3 ENOX1 GORASP2 LNX1 MAGEA11 MAGEA3 MLLT6 NDOR1 NTAQ1 RNF135 SNRPA SRPK2 STAMBPL1 TFIP11 TRAF5 TUBB4B VCL ZFP2
Entrez ID		4302	10495
HPRD ID		08978	02234
Ensembl ID		ENSG00000275023	ENSG00000165675
Uniprot IDs		P55198	A0A8I5KRI1 A0AAQ5BI24 Q16206 Q32ND0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Identical Protein Binding Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Polyubiquitin Modification-dependent Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Sequence-specific Double-stranded DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Chromatin Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Regulator Complex DNA-binding Transcription Factor Activity CAMP Response Element Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Neuron Differentiation Regulation Of Response To Endoplasmic Reticulum Stress Nucleus RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Protein Binding Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Cellular Response To Stress Aggresome Cis-trans Isomerase Activity Negative Regulation Of Store-operated Calcium Channel Activity Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Extrinsic Component Of Postsynaptic Early Endosome Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Integrated Stress Response Signaling Positive Regulation Of Response To Endoplasmic Reticulum Stress
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