ING5 and NAV2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		ING5	NAV2
Gene Name		inhibitor of growth family, member 5	neuron navigator 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm MOZ/MORF Histone Acetyltransferase Complex	Interstitial Matrix Nucleoplasm
	Molecular Function	Chromatin Binding Protein Binding Zinc Ion Binding Methylated Histone Binding	Helicase Activity ATP Binding Heparin Binding
	Biological Process	DNA Replication Chromatin Organization Transcription, DNA-templated Protein Acetylation Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Positive Regulation Of Apoptotic Signaling Pathway	Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Sensory Perception Of Sound Sensory Perception Of Smell Locomotory Behavior Metabolic Process Optic Nerve Development Glossopharyngeal Nerve Development Vagus Nerve Development
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		34 interactors: APC APLP1 ARFIP2 BARD1 C3orf62 CCDC33 CCDC67 CDCA7L CDKN1A CEP44 EP300 FAM118B GCSH HAP1 HGS HTT ICA1 IKZF3 JADE2 KIAA1377 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 PCM1 PRMT5 SMARCE1 TADA3 TAF1D TP53 VIM	10 interactors: ADAT2 APC CFAP58 ING4 ING5 MORF4L1 PIAS2 RBM15 RBM15B RRAS
Entrez ID		84289	89797
HPRD ID		16348	07385
Ensembl ID		ENSG00000168395	ENSG00000166833
Uniprot IDs		Q8WYH8	A7E2D6 Q8IVL1
PDB IDs		3C6W	2YRN
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Chromosome Organization Cell Cycle Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Cell Cycle Regulation Of Tubulin Deacetylation Histone Acetylation Mitotic Cell Cycle Phase Transition Internal Peptidyl-lysine Acetylation Cell Cycle Phase Transition Peptidyl-lysine Acetylation Cytoplasmic Microtubule Organization Chromatin Organization Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Gene Expression Cell Cycle Arrest Histone H3 Acetylation Regulation Of Protein Deacetylation Circadian Rhythm Chromatin Modification Stress-induced Premature Senescence Histone Modification Cell Aging Apoptotic Process Negative Regulation Of Gene Expression Tissue Development Central Nervous System Development Regulation Of Mitotic Cell Cycle Negative Regulation Of Biosynthetic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Mitotic Cell Cycle Arrest Programmed Cell Death Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Intracellular Transport Regulation Of Cellular Localization Regulation Of Cell Cycle Phase Transition Cell Death Death Nervous System Development Epithelium Development Determination Of Adult Lifespan	Peptidyl-lysine Modification Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Histone H3 Acetylation Histone H4 Acetylation Peptidyl-amino Acid Modification Histone Modification Chromosome Organization TRNA Wobble Adenosine To Inosine Editing Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Regulation Of Osteoblast Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Chromatin Modification Cell Cycle Arrest Positive Regulation Of Cell Death Regulation Of Growth Negative Regulation Of Odontogenesis Negative Regulation Of Cell Proliferation Positive Regulation Of Transcription Of Notch Receptor Target Immune System Development Regulation Of Myeloid Cell Differentiation Chromatin Organization Regulation Of RNA Metabolic Process Regulation Of Ossification Nucleobase-containing Compound Metabolic Process Metaphase/anaphase Transition Of Mitotic Cell Cycle Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Cellular Response To DNA Damage Stimulus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Growth Histone H4-K12 Acetylation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization DNA Replication Positive Regulation Of Pseudopodium Assembly DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Histone H4-K5 Acetylation Histone H4-K8 Acetylation Negative Regulation Of Androgen Receptor Signaling Pathway
Tagcloud ?		acetylates acetyllysine bonding bromodomain brpf1 calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally	amplifications analysing apc arid1a considerably copy epsilon excluding exome fam123b hypermethylation hypermutated igf2 integrative messenger microrna microsatellite mismatch mlh1 pik3ca pole quarter quarters rectum smad4 sox9 targetable tcf7l1 translocations
Tagcloud (Difference) ?		acetylates acetyllysine bonding bromodomain brpf1 calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally	amplifications analysing apc arid1a considerably copy epsilon excluding exome fam123b hypermethylation hypermutated igf2 integrative messenger microrna microsatellite mismatch mlh1 pik3ca pole quarter quarters rectum smad4 sox9 targetable tcf7l1 translocations
Tagcloud (Intersection) ?