MCAM and ATF7IP

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		MCAM	ATF7IP
Gene Name		melanoma cell adhesion molecule	activating transcription factor 7 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function		Transcription Corepressor Activity Protein Binding ATPase Activity
	Biological Process	Angiogenesis Glomerular Filtration Cell Adhesion Anatomical Structure Morphogenesis Positive Regulation Of Cell Migration Vascular Wound Healing	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Transcription, DNA-templated Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Pathways			Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		4 interactors: ADRB2 ATF7IP FYN PTK2B	68 interactors: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CSPG4 DISC1 DMTF1 DNM2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO3 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A
Entrez ID		4162	55729
HPRD ID		01120	09811
Ensembl ID		ENSG00000076706	ENSG00000171681
Uniprot IDs		P43121	B3KNI7 B3KQF8 F5GX74 G3V1U0 Q6VMQ6
PDB IDs			2RPQ
Enriched GO Terms of Interacting Partners?		Bone Resorption Peptidyl-tyrosine Autophosphorylation Bone Remodeling Regulation Of Bone Mineralization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Tissue Remodeling Positive Regulation Of Intracellular Signal Transduction Response To Ethanol Positive Regulation Of Protein Ubiquitination Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cell Shape Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Regulation Of CGMP-mediated Signaling Marginal Zone B Cell Differentiation Positive Regulation Of B Cell Chemotaxis Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Tissue Homeostasis Response To Abiotic Stimulus Regulation Of Ossification Negative Regulation Of Neuron Death Protein Autophosphorylation Regulation Of Protein Ubiquitination Response To Mechanical Stimulus Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Neuron Projection Development Regulation Of Neuron Apoptotic Process Multicellular Organismal Homeostasis Positive Regulation Of Signal Transduction Activation Of Janus Kinase Activity Activation Of Protein Kinase Activity Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Projection Organization Regulation Of Neuron Death Regulation Of Inositol Trisphosphate Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Heat Generation Diet Induced Thermogenesis Positive Regulation Of Neuron Differentiation Regulation Of Protein Complex Assembly Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Cellular Protein Complex Assembly Positive Regulation Of Cell Adhesion Regulation Of Neuron Projection Development Regulation Of Protein Catabolic Process Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain	Transcription Initiation From RNA Polymerase II Promoter Viral Process Positive Regulation Of Viral Transcription Cell Differentiation DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Regulation Of Viral Transcription 7-methylguanosine RNA Capping Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation RNA Biosynthetic Process Developmental Process Transcription, DNA-templated Anatomical Structure Development Regulation Of Viral Process Post-Golgi Vesicle-mediated Transport Macromolecule Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Gene Expression RNA Metabolic Process Extracellular Matrix Disassembly Cellular Macromolecule Biosynthetic Process Anatomical Structure Morphogenesis System Development Cell Junction Assembly Cardiovascular System Development Stem Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Biosynthetic Process Nervous System Development Neurogenesis Angiogenesis Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Golgi To Plasma Membrane Protein Transport Somatic Stem Cell Maintenance Protein Sumoylation Positive Regulation Of Gene Expression Multicellular Organismal Development Generation Of Neurons Stem Cell Development Blood Vessel Development Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Axon Guidance Golgi Vesicle Transport Vasculature Development
Tagcloud ?		adhesion baseline cec cecs cellsearch circulating combining correlations counts ctc ctcs cytometry deserves detection enriched enrichment epcam explored improve melanoma molecule nac neoadjuvant neozotac next pbc relevance separately starting	acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Difference) ?		adhesion baseline cec cecs cellsearch circulating combining correlations counts ctc ctcs cytometry deserves detection enriched enrichment epcam explored improve melanoma molecule nac neoadjuvant neozotac next pbc relevance separately starting	acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Intersection) ?