MCAM and SHROOM1

Number of citations of the paper that reports this interaction (PubMedID 19137261)
0

Data Source:
BioGRID (fluorescent resonance energy transfer)

		MCAM	SHROOM1
Description		melanoma cell adhesion molecule	shroom family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Membrane	Cytoplasm Cytoskeleton Microtubule Adherens Junction Apical Plasma Membrane Cortical Actin Cytoskeleton Apical Junction Complex
	Molecular Function	Laminin Receptor Activity Protein Binding	Actin Binding Myosin II Binding Actin Filament Binding
	Biological Process	Angiogenesis Glomerular Filtration Cell Adhesion Anatomical Structure Morphogenesis Positive Regulation Of Cell Migration Vascular Wound Healing	Cell Morphogenesis Actin Filament Bundle Assembly
Pathways		RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Plateletcrit ( 32888494)	Apolipoprotein A-IV levels ( 27412012) Asthma ( 31619474)
Interacting Genes		6 interacting genes: ADRB2 ATF7IP FYN LGALS3 PTK2B SHROOM1	2 interacting genes: CLK1 MCAM
Entrez ID		4162	134549
HPRD ID		01120	10655
Ensembl ID		ENSG00000076706	ENSG00000164403
Uniprot IDs		P43121	A6NN40 Q2M3G4
PDB IDs		6LYN
Enriched GO Terms of Interacting Partners?		Glutamate Receptor Signaling Pathway Regulation Of Metal Ion Transport Regulation Of Monoatomic Ion Transport Postsynaptic Density, Intracellular Component Bone Resorption Positive Regulation Of Excitatory Postsynaptic Potential Ionotropic Glutamate Receptor Signaling Pathway Regulation Of Calcium Ion Transport Vascular Endothelial Growth Factor Receptor Signaling Pathway Ligand-gated Ion Channel Signaling Pathway Cellular Response To Amyloid-beta Modulation Of Excitatory Postsynaptic Potential Peptidyl-tyrosine Phosphorylation Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Calcium Ion Import Response To Amyloid-beta Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Neurotransmitter Receptor Regulator Activity Cellular Response To Glycine Response To Singlet Oxygen Regulation Of Bone Mineralization Cell Body Positive Regulation Of Cellular Component Organization Multicellular Organismal-level Homeostasis Beta2-adrenergic Receptor Activity Negative Regulation Of Multicellular Organismal Process Modulation Of Chemical Synaptic Transmission Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of B Cell Chemotaxis Lymphocyte Activation Response To Glycine Positive Regulation Of Protein Localization To Membrane Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Disaccharide Binding Negative Regulation Of Immunological Synapse Formation Regulation Of Nervous System Process Regulation Of Ossification Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Leukocyte Activation Protein Tyrosine Kinase Activity Negative Regulation Of Hydrogen Peroxide Biosynthetic Process Negative Regulation Of NK T Cell Activation Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Regulation Of Multicellular Organismal Development Regulation Of Cell Shape Transmembrane Transporter Binding Norepinephrine Binding Positive Regulation Of Neuron Projection Development	Renal Filtration Laminin Receptor Activity Glomerular Filtration Angiogenesis Involved In Wound Healing Vascular Wound Healing Protein Serine/threonine/tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity
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