ATF7IP2 and FSD2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		ATF7IP2	FSD2
Name		activating transcription factor 7 interacting protein 2	fibronectin type III and SPRY domain containing 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Regulator Complex	Nucleus Cytoplasm Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Coregulator Activity	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription	None
GWAS		Copper levels ( 26025379 ) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644 ) Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644 ) Night sleep phenotypes ( 27126917 ) Response to antipsychotic treatment ( 20195266 )	HDL cholesterol levels ( 32203549 ) Hip circumference adjusted for BMI ( 34021172 ) Tourette syndrome ( 30818990 )
Interacting Genes		7 interacting genes: FSD2 MAP1LC3A MBD1 MED4 NUP62 SETDB1 SP1	93 interacting genes: AQP1 ARFIP2 ATF7IP2 ATG14 ATXN7L2 BEX2 BEX3 BRD8 C1orf216 CAMSAP3 CBX8 CCDC112 CCDC120 CCDC146 CCDC187 CCHCR1 CDC73 CDK18 CORO1A CTAG1A CTAG1B CWF19L2 DCX DTNB ENKD1 EXOC3 FAM107A FAM110A FAM161A FAM50B FAM90A1 FARS2 FMR1 HDAC4 HGS IFT20 KANSL1 KLHL40 LATS1 LENG1 LNX1 MCRS1 MID2 MRPL11 MYBPC2 NDN OIP5 OXNAD1 PBX3 PIK3R3 PNMA5 POLL PPP1R18 PPP2R5D PRPF18 PRPF31 PSMB4 RCOR3 RNF8 SCNM1 SH2D4A SMARCE1 SNAPIN SPATC1L TCEANC THAP7 TLE5 TSGA10IP TTC23 UBTFL1 VEZF1 ZBTB38 ZC2HC1C ZMAT2 ZNF124 ZNF20 ZNF230 ZNF35 ZNF408 ZNF410 ZNF417 ZNF490 ZNF572 ZNF580 ZNF581 ZNF587 ZNF648 ZNF76 ZNF774 ZNF777 ZNF835 ZNF837 ZSCAN26
Entrez ID		80063	123722
HPRD ID		16517	17291
Ensembl ID		ENSG00000166669	ENSG00000186628
Uniprot IDs		Q5U623	A1L4K1 B7ZM05
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		DNA Methylation-dependent Constitutive Heterochromatin Formation Constitutive Heterochromatin Formation Positive Regulation Of Hydrogen Sulfide Biosynthetic Process Cellular Response To Wortmannin Double-stranded Methylated DNA Binding Heterochromatin Formation Negative Regulation Of Gene Expression, Epigenetic Cellular Response To Starvation Response To Wortmannin Cellular Response To Zinc Ion Starvation Histone H3K9 Trimethyltransferase Activity Histone H3K9 Monomethyltransferase Activity PTB Domain Binding Phospholipid Binding Nuclear Pore Central Transport Channel Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of Protein Localization To Centrosome Mitotic Centrosome Separation Response To Iron(II) Ion Cellular Response To Oxygen-glucose Deprivation	Zinc Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Gene Expression Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Identical Protein Binding Regulation Of Metabolic Process Centriole Microtubule Anchoring Microtubule Binding