TBC1D3B and GTPBP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TBC1D3B	GTPBP3
Description		TBC1 domain family member 3B	GTP binding protein 3, mitochondrial
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Membrane	Nucleus Cytoplasm Mitochondrion Transferase Complex
	Molecular Function	GTPase Activator Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity TRNA 5-taurinomethyluridine Synthase Activity
	Biological Process		TRNA Wobble Uridine Modification TRNA Modification TRNA Processing TRNA Methylation Mitochondrial TRNA Wobble Uridine Modification
Pathways			tRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Body mass index ( 26426971) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Mitochondrial DNA copy number ( 30704525)
Interacting Genes		9 interacting genes: BAG3 BAG4 GEM GRB2 GTPBP3 HSPB1 MDFI PSMD2 ZRANB1	29 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD OGT PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774
Entrez ID		414059	84705
HPRD ID		11264	12255
Ensembl ID		ENSG00000274808	ENSG00000130299
Uniprot IDs		A6NDS4	B7Z563 Q969Y2
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Protein Transport Along Microtubule Adenyl-nucleotide Exchange Factor Activity Nucleus Protein Folding Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Actin Filament Polymerization Guanyl-nucleotide Exchange Factor Adaptor Activity Negative Regulation Of Protein Kinase C Signaling Proteasome Complex Negative Regulation Of MRNA Modification Positive Regulation Of Protein Polymerization Grb2-EGFR Complex Response To Unfolded Protein Response To Heat Proteasome Storage Granule Autophagosome Assembly TRNA 5-taurinomethyluridine Synthase Activity Mitochondrial TRNA Wobble Uridine Modification Protein-folding Chaperone Binding Autophagosome Organization Protein Kinase C Inhibitor Activity Cell Surface Receptor Signaling Pathway Regulation Of Actin Filament Polymerization Z Disc Protein K29-linked Deubiquitination Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Protein Kinase C Signaling Negative Regulation Of Establishment Of Protein Localization Positive Regulation Of Aggrephagy Protein K33-linked Deubiquitination Response To Temperature Stimulus Neurotrophin TRKA Receptor Binding Aggresome Assembly Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Supramolecular Fiber Organization Transport Along Microtubule Chaperone-mediated Autophagy Vacuole Organization
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