MAN2A2 and ELP1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MAN2A2	ELP1
Description		mannosidase alpha class 2A member 2	elongator acetyltransferase complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Nucleus Cytoplasm Cytosol Elongator Holoenzyme Complex
	Molecular Function	Catalytic Activity Alpha-mannosidase Activity Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase Activity Protein Binding Mannosidase Activity Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Hydrolase Activity, Hydrolyzing N-glycosyl Compounds Carbohydrate Binding Metal Ion Binding	TRNA Binding Protein Binding
	Biological Process	Carbohydrate Metabolic Process Mannose Metabolic Process Protein Glycosylation N-glycan Processing	TRNA Wobble Uridine Modification TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Regulation Of Translation TRNA Processing
Pathways		Intra-Golgi traffic Reactions specific to the complex N-glycan synthesis pathway	HATs acetylate histones
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Brain morphology (MOSTest) ( 32665545) Caffeine consumption from coffee ( 33287642) Schizophrenia ( 25056061 29483656)	Appendicular lean mass ( 33097823)
Interacting Genes		6 interacting genes: CHD3 ELP1 ENO3 GIT1 LUC7L2 VIM	27 interacting genes: BAG6 BARD1 CCT5 CDKN2B CHUK CSTF2 ELP2 ELP3 ELP6 HTT IKBKB IRF4 MAN2A2 MAP3K14 MAP3K7 MAPK8 MRPL42 NDUFB9 NFKBIA NIPSNAP3A PBX2 PLP2 SDHAF2 SNAPIN TAC3 TTR TXNDC9
Entrez ID		4122	8518
HPRD ID		02994	04763
Ensembl ID		ENSG00000196547	ENSG00000070061
Uniprot IDs		A0A0C4DGL1 H0YNG5 P49641	A0A6Q8PGW3 A0A6Q8PHA0 B3KNB2 B4E3I9 F5H2T0 O95163 Q8N516
PDB IDs			5CQR 8PTX 8PTY 8PTZ 8PU0
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Microtubule Polymerization Centrosome Cycle Regulation Of Microtubule Polymerization Scaffold Protein Binding Negative Regulation Of ARF Protein Signal Transduction Microtubule Organizing Center Organization Positive Regulation Of Protein Polymerization Regulation Of Microtubule Polymerization Or Depolymerization Focal Adhesion Cellular Response To Lipid Structural Constituent Of Postsynaptic Specialization	Non-canonical NF-kappaB Signal Transduction Elongator Holoenzyme Complex TRNA Wobble Uridine Modification Immune Response-regulating Signaling Pathway Canonical NF-kappaB Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway IkappaB Kinase Activity Fc-epsilon Receptor Signaling Pathway Stress-activated MAPK Cascade Innate Immune Response-activating Signaling Pathway Stress-activated Protein Kinase Signaling Cascade Interleukin-1-mediated Signaling Pathway Cellular Response To Tumor Necrosis Factor Activation Of Innate Immune Response Immune Response-activating Signaling Pathway Cytoplasmic Pattern Recognition Receptor Signaling Pathway Signal Transduction Involved In Regulation Of Gene Expression Response To Tumor Necrosis Factor Immune Response-activating Cell Surface Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Activation Of Immune Response Cell Surface Toll-like Receptor Signaling Pathway IkappaB Kinase Complex Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Innate Immune Response Regulation Of Immune Response Cell Surface Pattern Recognition Receptor Signaling Pathway Fc Receptor Signaling Pathway Positive Regulation Of Innate Immune Response Tumor Necrosis Factor-mediated Signaling Pathway CD40 Receptor Complex Transferrin Receptor Binding TRIF-dependent Toll-like Receptor Signaling Pathway Cytosol Scaffold Protein Binding MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MAP Kinase Activity Regulation Of Cytokine Production Involved In Inflammatory Response TRNA Modification Protein Serine/threonine Kinase Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Immune Response Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?