MAGEB2 and RPGRIP1

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		MAGEB2	RPGRIP1
Name		MAGE family member B2	RPGR interacting protein 1
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol Cytoskeleton Cilium Axoneme Microtubule Cytoskeleton Photoreceptor Connecting Cilium Cell Projection Neuron Projection Intercellular Bridge Non-motile Cilium Photoreceptor Distal Connecting Cilium
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Visual Perception Eye Photoreceptor Cell Development Retinal Rod Cell Development Retina Development In Camera-type Eye Neural Precursor Cell Proliferation Non-motile Cilium Assembly
Diseases		None	Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		No GWAS studies recorded	Body mass index ( 26426971 ) Body mass index (age>50) ( 26426971 ) Body mass index x sex x age interaction (4df test) ( 26426971 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Height ( 31562340 ) Refractive error ( 32231278 ) Superior temporal sulcus banks volume ( 31530798 )
Interacting Genes		9 interacting genes: ARID3A ATXN1 CCNL2 CFTR ECSIT PRMT5 RPGRIP1 TXN2 ZBED1	26 interacting genes: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RNF6 RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564 ZNF688
Entrez ID		4113	57096
HPRD ID		02109	05673
Ensembl ID		ENSG00000099399	ENSG00000092200
Uniprot IDs		O15479 Q53G50	Q96KN7
PDB IDs		Not available	4QAM
GO Terms Enriched among Interactors		Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Gliogenesis Protein Autosumoylation Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Positive Regulation Of Anion Channel Activity Positive Regulation Of Monoatomic Anion Transport Regulation Of Gliogenesis Peptidyl-arginine N-methylation Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Photoreceptor Distal Connecting Cilium	Regulation Of DNA-templated Transcription Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Nucleus Regulation Of RNA Biosynthetic Process Ciliary Basal Body