MAGEB2 and CCNL2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		MAGEB2	CCNL2
Name		MAGE family member B2	cyclin L2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Protein Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Centrosome Cycle Regulation Of Cell Cycle
GWAS		No GWAS studies recorded	Inflammatory bowel disease ( 28067908 ) Ulcerative colitis ( 28067908 )
Interacting Genes		9 interacting genes: ARID3A ATXN1 CCNL2 CFTR ECSIT PRMT5 RPGRIP1 TXN2 ZBED1	15 interacting genes: CDK11B DYRK1A EMD FAM90A1 KRTAP12-2 MAGEB2 MDFI PIH1D2 POLR2A RUNDC3A SRSF2 SRSF7 TRIM41 USP20 ZBTB7B
Entrez ID		4113	81669
HPRD ID		02109	10815
Ensembl ID		ENSG00000099399	ENSG00000221978
Uniprot IDs		O15479 Q53G50	Q96S94
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Gliogenesis Protein Autosumoylation Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Positive Regulation Of Anion Channel Activity Positive Regulation Of Monoatomic Anion Transport Regulation Of Gliogenesis Peptidyl-arginine N-methylation Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Photoreceptor Distal Connecting Cilium	Regulation Of RNA Splicing Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of RNA Splicing Negative Regulation Of RNA Metabolic Process Histone H3T45 Kinase Activity TMEM240-body Negative Regulation Of NK T Cell Proliferation