COL9A1 and COMP

Number of citations of the paper that reports this interaction (PMID 15047691)
12

Data Source:
HPRD (in vitro)

		COL9A1	COMP
Gene Name		collagen, type IX, alpha 1	cartilage oligomeric matrix protein
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Collagen Type IX Trimer Endoplasmic Reticulum Lumen	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Extracellular Matrix Structural Constituent Conferring Tensile Strength Metal Ion Binding	Protease Binding Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Collagen Binding Heparin Binding Heparan Sulfate Proteoglycan Binding
	Biological Process	Tissue Homeostasis Growth Plate Cartilage Development Axon Guidance Organ Morphogenesis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process	Skeletal System Development Growth Plate Cartilage Development Apoptotic Process Cell Adhesion Organ Morphogenesis Extracellular Matrix Organization Negative Regulation Of Apoptotic Process Limb Development
Pathways		Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Degradation of the extracellular matrix ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth	ECM proteoglycans Integrin cell surface interactions
Drugs			Calcium
Diseases
GWAS
Protein-Protein Interactions		3 interactors: COL2A1 COMP MAG	4 interactors: COL2A1 COL9A1 FN1 OTX1
Entrez ID		1297	1311
HPRD ID		00367	02632
Ensembl ID		ENSG00000112280	ENSG00000105664
Uniprot IDs		B3KWS8 P20849	B4DKJ3 P49747
PDB IDs		2UUR	3FBY
Enriched GO Terms of Interacting Partners?		Cartilage Development Involved In Endochondral Bone Morphogenesis Endochondral Bone Morphogenesis Bone Morphogenesis Cartilage Development Limb Development Bone Development Connective Tissue Development Skeletal System Morphogenesis Extracellular Matrix Organization Extracellular Structure Organization Limb Bud Formation Skeletal System Development Cellular Response To Growth Factor Stimulus Response To Growth Factor Otic Vesicle Development Organ Development Growth Plate Cartilage Development Embryonic Skeletal Joint Morphogenesis Embryonic Skeletal Joint Development Notochord Development Cartilage Condensation Cellular Response To BMP Stimulus Endochondral Bone Growth Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Substantia Nigra Development Central Nervous System Development Negative Regulation Of Cell Death Organ Morphogenesis Endochondral Ossification System Development Neural Nucleus Development Cell Adhesion Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Collagen Fibril Organization Negative Regulation Of Axonogenesis Collagen Catabolic Process Locomotion Multicellular Organismal Development Anatomical Structure Development Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Chondrocyte Differentiation Midbrain Development Regulation Of Apoptotic Process Multicellular Organismal Metabolic Process Movement Of Cell Or Subcellular Component Extracellular Matrix Disassembly Regulation Of Cell Death	Extracellular Matrix Disassembly Cartilage Development Involved In Endochondral Bone Morphogenesis Extracellular Matrix Organization Extracellular Structure Organization Collagen Catabolic Process Collagen Metabolic Process Endochondral Bone Morphogenesis Multicellular Organismal Macromolecule Metabolic Process Embryonic Morphogenesis Multicellular Organismal Metabolic Process Nervous System Development Inner Ear Morphogenesis Cell Morphogenesis Involved In Differentiation Anatomical Structure Morphogenesis Bone Morphogenesis Ear Morphogenesis Organ Morphogenesis Tissue Homeostasis Cell Morphogenesis Inner Ear Development Cartilage Development Embryo Development Bone Development Locomotion Ear Development Multicellular Organismal Homeostasis Calcium-independent Cell-matrix Adhesion Connective Tissue Development Skeletal System Morphogenesis Movement Of Cell Or Subcellular Component System Development Diencephalon Morphogenesis Embryonic Organ Morphogenesis Generation Of Neurons Neurogenesis Tissue Development Axon Guidance Limb Bud Formation Multicellular Organismal Development Cell Development Anatomical Structure Development Integrin Activation Embryonic Organ Development Otic Vesicle Development Axonogenesis Developmental Process Growth Plate Cartilage Development Skeletal System Development Embryonic Skeletal Joint Morphogenesis Axon Development
Tagcloud ?		ablation aggrecan betaig cartilage chondrocyte collagen comp compensatory disturbed endochondral epiphycan epiphyseal fibronectin hypocellular interactome ix knock matn3 matrilin null oligomeric osteoarthritis proteomic tgfbeta thrombospondin underpinning xii	20e ab11 acari amblyomma basepair ecdysone ecdysteroid ecdysteroids ecr ecre ecres endocrinol hebraeum heterodimerized hsp27 ixodid ixodidae kaufman koch mak mcblain mur palindrome pon ponasterone salivary supershifted tick usp
Tagcloud (Difference) ?		ablation aggrecan betaig cartilage chondrocyte collagen compensatory disturbed endochondral epiphycan epiphyseal fibronectin hypocellular interactome ix knock matn3 matrilin null oligomeric osteoarthritis proteomic tgfbeta thrombospondin underpinning xii	20e ab11 acari amblyomma basepair ecdysone ecdysteroid ecdysteroids ecr ecre ecres endocrinol hebraeum heterodimerized hsp27 ixodid ixodidae kaufman koch mak mcblain mur palindrome pon ponasterone salivary supershifted tick usp
Tagcloud (Intersection) ?		comp